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Higher-Order Chromatin Architecture in Time and Space

November 15-17, 2021 | 10:00AM EST | 3:00PM UTC | 4:00PM UTC*
*Program is in development and subject to change


The live portion of this conference has concluded and all presentations are now available for purchase on demand. Registrants to the live event may access this content anytime for up to 9 months following the event.

 Free Access to On Demand Content to Scientists from Low-and Middle-Income Countries

Keystone Symposia welcomes the global scientific community and aims to connect researchers within and across disciplines to accelerate the advancement of biomedical and life sciences. This form may be used for scientists from low- and middle-income countries of all career stages to determine eligibility and request free access to scientific content presented during recent eSymposia events. If eligible, you will be sent an access code for the On Demand content of the eSymposia event(s) of interest.

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Mammalian genomes are folded in a hierarchy of compartments, topologically associating domains (TADs), subTADs, and looping interactions. As genome-wide chromatin architecture maps become widely available, the field is shifting focus from mapping to understanding the dynamics of such structures in development, the cell cycle, and on short time scales in single cells. A critical emerging goal will be to unravel the cause and effect relationship between genome folding and functions such as transcription, replication, recombination, and stability/maintenance. There is also a great need to evaluate the organizing principles governing chromatin topology across many biological conditions and genetic perturbations. Moreover, the role for 3D genome misfolding in the onset and progression of a wide range of human disease states remains an area of high interest across multiple disciplines and organ systems.  Overall, this Keystone eSymposia virtual event is meant to highlight new frontiers across disciplines in tackling the dynamics and functional roles of the 3D genome in cellular functions across time and space in development and disease.

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Regular Registration Rate: $275 USD
Student Registration Rate: $150 USD


Abstract Submission
‣ For Short Talk Consideration: Oct. 4, 2021
‣ For ePoster Presentation: Nov. 1, 2021
Final ePoster/SciTalk Submission: Nov. 5, 2021
Financial Aid Application: Nov. 1, 2021

*Abstract submission is required in order to submit an ePoster and/or Scitalk


Financial Aid Opportunities

Graduate students and postdoctoral fellows, as well as individuals from low- and middle-income countries (all career stages) working in science and medicine-related fields, are eligible to apply for a FREE registration code.

Find out more about financial aid opportunities here!

Call For Abstracts

Showcase your work to global audiences on the eSymposia platform!

Submit your abstract by the Short Talk Deadline for the opportunity to be selected for a short talk presentation alongside field leaders on the meeting program!

ePoster presenters will be provided with their own dedicated abstract listing on the event website to display their work in multiple formats, and interact with meeting participants. ePoster features include:

  • Abstract Description
  • An embedded ePoster with an optional downloadable PDF
  • SciTalk – up to 5-minute video presentation, available on demand
  • A poster table at the Live Poster Session to present your work and answer audience questions in real-time
  • A chat function to speak with interested attendees and answer questions throughout the conference
  • Contact information for private follow-up discussion

To submit your work for an ePoster presentation, and to be considered for short talk selection, go to the Submit an Abstract tab on the event homepage.

Program Details

Keynote Speaker

[Pedro L. Alonso, MD, PhD]

[Pedro L. Alonso, MD, PhD]
[World Health Organization, Director of the Global Malaria Programme]

Speaking at this eSymposia

Gerd A. Blobel

Children's Hospital of Philadelphia, USA

Clifford P. Brangwynne

Princeton University, USA

Benoit G. Bruneau

Gladstone Institutes, USA

Bradley R. Cairns

HHMI/University of Utah, USA

Daniele Canzio

University of California, San Francisco, USA

Job Dekker

University of Massachusetts Medical School, USA

Suzana Hadjur

University College London, UK

Nancy E. Kleckner

Harvard University, USA

Jeannie T. Lee

Massachusetts General Hospital/Harvard Medical School, USA

Erez Lieberman-Aiden

Baylor College of Medicine, USA

Stavros Lomvardas

Columbia University, USA

Leonid Mirny

Massachusetts Institute of Technology, USA

Clodagh C. O'Shea

The Salk Institute for Biological Studies, USA

Jennifer E. Phillips-Cremins

University of Pennsylvania, USA

Ana Pombo

Max-Delbrück-Centrum für Molekulare Medizin, Germany

Karen L. Reddy

Johns Hopkins University, USA

Bing Ren

Ludwig Institute for Cancer Research, USA

François Spitz

Institut Pasteur, France

Amos Tanay

Weizmann Institute, Israel

Bas van Steensel

Netherlands Cancer Institute, Netherlands

Ting (C.-ting) Wu

Harvard Medical School, USA

Xiaowei Zhuang

Harvard University, USA





Additional Support




Funding for this conference was made possible (in part) by Grant No. [GRANT NUMBER - UPDATE] from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

Media-in-Kind Support










The views expressed in this eSymposia are those of the participants and not necessarily of the participants’ organizations or of Keystone Symposia.


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