This ePanel will celebrate the inaugural winners of the Michelson Philanthropies & Science Prize for Immunology, an international prize that focuses on transformative research in human immunology, with trans-disease applications to accelerate vaccine and immunotherapeutic discovery…

There is a need for wastewater based epidemiological (WBE) methods that integrate multiple,

Genome-wide association studies have identified genes modulating microglia and inflammation to be associated with an enhanced risk for Alzheimer’s disease (AD). Furthermore, increased microglial activation has been associated with the progression of AD…

Advancing Nose-to-Brain Delivery of Nucleic Acids through Localization

Recently, the team at DeepMind has released a deep learning based protein folding structure prediction algorithm called Alphafold2. This algorithm has achieved remarkable scores at the CASP14 competition, and in many cases achieves remarkable accuracy…

Neural mechanism underlying the anti-nausea effect of GIP

B cells contribute to multiple aspects of autoimmune disorders through autoantibody production, antigen presentation, cytokine secretion, and formation of tertiary lymphoid structures. B cell targeting therapies have been developed and approved for treatment of autoimmune diseases…

Upon subcutaneous (SQ) injection of therapeutic drugs, a local inflammatory reaction, commonly referred to as an injection site reaction (ISR), may develop at the injection site. ISRs are characterized by one or more of the following, erythema, edema, pruritus, pain, and induration…

During a new pandemic such as COVID-19, there is a need to develop drug treatments as quickly as possible. However, a new disease means that limited information would be available…

Drug discovery and development is a costly and lengthy process that involves balancing multiple attributes of molecules to achieve desired clinical efficacy and safety…