March 24-25, 2021 | 10:00AM EDT | 2:00PM UTC | 3:00PM CET*
*Program is in development and subject to change
The live portion of this conference has concluded and all presentations are now available for purchase on demand. Registrants to the live event may access this content anytime for up to 9 months following the event.
Keystone Symposia welcomes the global scientific community and aims to connect researchers within and across disciplines to accelerate the advancement of biomedical and life sciences. This form may be used for scientists from low- and middle-income countries of all career stages to determine eligibility and request free access to scientific content presented during recent eSymposia events. If eligible, you will be sent an access code for the On Demand content of the eSymposia event(s) of interest.
Metabolism was once regarded as a homeostatic, housekeeping process that supported but did not instruct cell signaling, gene expression and other networks. In recent years, it has become apparent that metabolism is intimately intertwined with many other networks that determine cellular fate and tissue function, and that metabolites can transmit signals within and between cells. The impact of metabolic signaling is illustrated by the consequences of its dysregulation; we now understand that many diseases involve pathologically altered metabolism. Mutations in metabolic enzymes underlie numerous developmental disorders, and metabolic alterations in malignant cells impair cellular differentiation and fuel tumor growth. These observations have rekindled interest in disease-oriented metabolism research, which now benefits from increasingly sophisticated analytical and computational tools to understand metabolism and to localize important activities in space and time. With this new symposium, we aim to capitalize on both the technological and conceptual momentum of this budding field.
The unifying theme of this symposium is that proper development requires exquisite metabolic control, and that perturbed metabolism can result in developmental diseases. The symposium will bring together scientists exploring how metabolites impact cellular and developmental decisions in a diverse range of model systems, and mechanisms underlying developmental disorders caused by aberrant metabolism. Topics will include – but need not be confined to – the epigenetic roles of metabolites and their oncogenic potential, signalling roles of metabolites across organs, metabolic control of development, and the impact of microbiota-mediated signaling in ageing and metabolic disease. Collectively, we hope to foster collaborations across a range of disciplines, provide biological questions for emerging technologies, and ultimately develop a new conceptual framework for the study of the instructive roles of metabolites in biology and disease.
Regular Registration Rate: $275 USD
Student Registration Rate: $150 USD
Abstract Submission:
‣ For Short Talk Consideration: Passed
‣ For Poster Booth: Passed
ePoster / SciTalk Submission: Passed
Financial Aid Application: Passed
*Abstract submission is required in order to submit an ePoster and/or Scitalk
#VKSMetaDisease21
Olivier Pourquié
Harvard Medical School
Theodore Alexandrov
European Molecular Biology Laboratory, Germany
Alexander Aulehla
European Molecular Biology Laboratory, Germany
Navdeep S. Chandel
Northwestern University, USA
Heather Christofk
University of California, Los Angeles, USA
Ralph J. DeBerardinis
University of Texas Southwestern Medical Center, USA
Ayelet Erez
Weizmann Institute of Science, Israel
Sarah-Maria Fendt
VIB Leuven, Belgium
Lydia Finley
Memorial Sloan Kettering Cancer Center, USA
Wendy S. Garrett
Harvard School of Public Health, USA
Alex Gould
Francis Crick Institute, UK
Lora V. Hooper
University of Texas Southwestern Medical Center, USA
Jason Locasale
Duke University School of Medicine, USA
Irene Miguel-Aliaga
Imperial College London, UK
Norbert Perrimon
Harvard Medical School, USA
Olivier Pourquié
Harvard Medical School, USA
Joshua D. Rabinowitz
Princeton University, USA
Markus Ralser
Francis Crick Institute, UK
Jared Rutter
University of Utah, USA
Aurelio Teleman
Deutsches Krebsforschungszentrum, Germany
Tadashi Uemura
Kyoto University, Japan
A.J. Marian Walhout
University of Massachusetts Medical School, USA
Kathryn E. Wellen
University of Pennsylvania, USA
This new virtual meeting format came out of difficult circumstances, but your commitment to scientific progress is what inspired us to launch Keystone eSymposia. In these virtual meetings, we are capturing the same innovative essence of our in-person meetings that you've all created as a scientific community. Here, Debbie Johnson, our CEO, explains how we're going to do that.
The views expressed in this eSymposia are those of the participants and not necessarily of the participants’ organizations or of Keystone Symposia.