Hematopoiesis
April 21-23, 2021 | 10:00AM EDT | 2:00PM UTC | 4:00PM CEST*
*Program is in development and subject to change
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Showing results 1 - 9 of 9
Wednesday, April 21, 2021
Welcome and Keynote Address
10:00 AM - 10:40 AM EDT
Wednesday, April 21, 2021Room: V200 - Ian Loudon Organizer
Daniel Starczynowski, PhD
Cincinnati Children's Hospital Medical Center
Keynote
Benjamin Ebert, MD, PhD
Dana-Farber Cancer Institute
Welcome and Keynote Address
Clonal Hematopoiesis in Hematologic Malignancies and Cardiovascular Disease
10:00 AM - 10:40 AM EDT
Wednesday, April 21, 2021Room: V200 - Ian Loudon Speaker
Benjamin Ebert, MD, PhD
Dana-Farber Cancer Institute
Welcome and Keynote Address
Hematopoiesis during Stress and Aging
10:40 AM - 1:00 PM EDT
Wednesday, April 21, 2021Room: Multi-Room Split Session Co-Chairs
Katherine King, MD, PhD
Baylor College of Medicine
Jennifer Trowbridge, PhD
The Jackson Laboratory
Speakers
Ido Amit, PhD
Weizmann Institute
H. Leighton Grimes, PhD
Cincinnati Children's Hospital Medical Center
Anna Beaudin, PhD
University of Utah School of Medicine
Serine Avagyan, MD, PhD
Boston Children’s Hospital Cancer and Blood Disorders Center
Hematopoiesis during Stress and Aging
The Power of ONE: Immunology in the Age of Single Cell Genomics
10:40 AM - 11:05 AM EDT
Wednesday, April 21, 2021Room: V300 - Chad Littman Speaker
Ido Amit, PhD
Weizmann Institute
Hematopoiesis during Stress and Aging
Infection Is a Driver of Dnmt3a-Mutant Clonal Hematopoiesis
11:05 AM - 11:30 AM EDT
Wednesday, April 21, 2021Room: V300 - Chad Littman Speaker
Katherine King, MD, PhD
Baylor College of Medicine
Hematopoiesis during Stress and Aging
Coffee Break
11:30 AM - 11:40 AM EDT
Wednesday, April 21, 2021Hematopoiesis during Stress and Aging
Microenvironmental Regulation of HSC Aging
11:40 AM - 12:05 PM EDT
Wednesday, April 21, 2021Room: V100 - Ben Schramm Speaker
Jennifer Trowbridge, PhD
The Jackson Laboratory
Hematopoiesis during Stress and Aging
Transitional States in Hematopoiesis
12:05 PM - 12:30 PM EDT
Wednesday, April 21, 2021Room: V100 - Ben Schramm Speaker
H. Leighton Grimes, PhD
Cincinnati Children's Hospital Medical Center
Hematopoiesis during Stress and Aging
Short Talk: Prenatal Inflammation Perturbs Fetal Hematopoiesis and Causes Persistent Changes to Postnatal Immunity
12:30 PM - 12:45 PM EDT
Wednesday, April 21, 2021Room: V100 - Ben Schramm Speaker
Anna Beaudin, PhD
University of Utah School of Medicine
Hematopoiesis during Stress and Aging
Short Talk: Clonal Hematopoiesis Results from the Response of Stem and Progenitor Cells to Inflammatory Cues from Mutant Mature Cells
12:45 PM - 1:00 PM EDT
Wednesday, April 21, 2021Room: V100 - Ben Schramm Speaker
Serine Avagyan, MD, PhD
Boston Children’s Hospital Cancer and Blood Disorders Center
Hematopoiesis during Stress and Aging
Career Roundtable
2:30 PM - 3:30 PM EDT
Wednesday, April 21, 2021Panelists
Fernando Camargo, PhD
Boston Children's Hospital
Hanna Mikkola, MD, PhD
University of California, Los Angeles
Daniel Starczynowski, PhD
Cincinnati Children's Hospital Medical Center
Keystone Symposia Roundtables
Microenvironment and Signaling
5:00 PM - 8:00 PM EDT
Wednesday, April 21, 2021Room: Multi-Room Split Session Co-Chairs
Kateri Moore, DVM
Ichan School of Medicine at Mount Sinai
Timm Schroeder, PhD
ETH Zürich
Speakers
Cristina Lo Celso, PhD
Imperial College London; Sir Francis Crick Institute
Sean Morrison, PhD
University of Texas Southwestern Medical Center
Sisi Chen, PhD
Memorial Sloan Kettering Cancer Center
Adil Rasheed, PhD
University of Ottawa Heart Institute
Anthony Ho, MD
Heidelberg University
Christina Termini, PhD
University of California, Los Angeles
Zanshe Thompson, MS
University of South Carolina
Melissa Meyer, PhD
La Jolla Institute for Immunology
Microenvironment and Signaling
Long-Term Single-Cell Quantification: New Tools for Old Questions
5:00 PM - 5:30 PM EDT
Wednesday, April 21, 2021Room: V300 - Chad Littman Speaker
Timm Schroeder, PhD
ETH Zürich
Microenvironment and Signaling
Microenvironmental Regulation of HSC Function
5:30 PM - 6:00 PM EDT
Wednesday, April 21, 2021Room: V300 - Chad Littman Speaker
Cristina Lo Celso, PhD
Imperial College London; Sir Francis Crick Institute
Microenvironment and Signaling
Coffee Break
6:05 PM - 6:30 PM EDT
Wednesday, April 21, 2021Microenvironment and Signaling
Niche Biology: Beyond Growth Factors
6:30 PM - 6:55 PM EDT
Wednesday, April 21, 2021Room: V300 - Chad Littman Speaker
Sean Morrison, PhD
University of Texas Southwestern Medical Center
Microenvironment and Signaling
Short Talk: Altered LZTR1 and RIT1 Signaling Drive Clonal Hematopoietic Transformation
6:55 PM - 7:10 PM EDT
Wednesday, April 21, 2021Room: V100 - Ben Schramm Speaker
Sisi Chen, PhD
Memorial Sloan Kettering Cancer Center
Microenvironment and Signaling
Short Talk: Mixed Lineage Kinase Domain-Like Protein (MLKL) Maintains the Splenic Microenvironment to Restrict Hematopoiesis During Atherosclerosis
7:10 PM - 7:25 PM EDT
Wednesday, April 21, 2021Room: V100 - Ben Schramm Speaker
Adil Rasheed, PhD
University of Ottawa Heart Institute
Microenvironment and Signaling
Short Talk: Hematopoietic Stem Cells with Elevated Central Carbon Metabolism Drive the Aging Process and Harbor Clonal Hematopoiesis
7:25 PM - 7:40 PM EDT
Wednesday, April 21, 2021Room: V100 - Ben Schramm Speaker
Anthony Ho, MD
Heidelberg University
Microenvironment and Signaling
Short Talk: Semaphorin 3A Controls Bone Marrow Vascular Regeneration and Hematopoietic Reconstitution
7:40 PM - 7:55 PM EDT
Wednesday, April 21, 2021Room: V100 - Ben Schramm Speaker
Christina Termini, PhD
University of California, Los Angeles
Microenvironment and Signaling
Short Talk: Ing4 Suppresses Quiescence and Inflammation in Hematopoietic Stem Cells
7:55 PM - 8:10 PM EDT
Wednesday, April 21, 2021Room: V100 - Ben Schramm Speaker
Zanshe Thompson, MS
University of South Carolina
Microenvironment and Signaling
Short Talk: Discovery of a Neutrophil Subset with B Cell Features and the Ability to Modulate CD4+ T Cells
8:10 PM - 8:25 PM EDT
Wednesday, April 21, 2021Room: V100 - Ben Schramm Speaker
Melissa Meyer, PhD
La Jolla Institute for Immunology
Microenvironment and Signaling
Thursday, April 22, 2021
HSC Biology and Development
10:00 AM - 1:05 PM EDT
Thursday, April 22, 2021Room: Multi-Room Split Session Co-Chairs
Hanna Mikkola, MD, PhD
University of California, Los Angeles
Fernando Camargo, PhD
Boston Children's Hospital
Speakers
Shannon McKinney-Freeman, PhD
St. Jude Children's Research Hospital
E. Camilla Forsberg, PhD
University of California, Santa Cruz
Leonard Zon, MD
HHMI/Boston Children's Hospital
Catherine Rhee, PhD
Harvard University/ MGH
Grant Rowe, MD, PhD
Boston Children's Hospital
YeEun Kim, BS
Stanford
Bianca Ulloa, MS
Albert Einstein College of Medicine
Hiromitsu Nakauchi
Stanford University
HSC Biology and Development
Assessing HSC Potential in vivo at the Single Cell Level
10:00 AM - 10:25 AM EDT
Thursday, April 22, 2021Room: V300 - Chad Littman Speaker
Fernando Camargo, PhD
Boston Children's Hospital
HSC Biology and Development
Ontogeny of the Hematopoietic Hierarchy
10:25 AM - 10:50 AM EDT
Thursday, April 22, 2021Room: V300 - Chad Littman Speaker
Shannon McKinney-Freeman, PhD
St. Jude Children's Research Hospital
HSC Biology and Development
Chasing Mavericks: The Quest to Understand Hematopoietic Stem Cell Waves
10:50 AM - 11:15 AM EDT
Thursday, April 22, 2021Room: V300 - Chad Littman Speaker
E. Camilla Forsberg, PhD
University of California, Santa Cruz
HSC Biology and Development
Coffee Break
11:15 AM - 11:25 AM EDT
Thursday, April 22, 2021HSC Biology and Development
Embryonic Macrophage-Hematopoietic Stem Cell Interactions Determine Adult
11:25 AM - 11:50 AM EDT
Thursday, April 22, 2021Room: V100 - Ben Schramm Speaker
Leonard Zon, MD
HHMI/Boston Children's Hospital
HSC Biology and Development
Short Talk: Rigidity of Cell Fate and Function among Monocytes
11:50 AM - 12:05 PM EDT
Thursday, April 22, 2021Room: V100 - Ben Schramm Speaker
Catherine Rhee, PhD
Harvard University/ MGH
HSC Biology and Development
Short Talk: Hematopoiesis at Single Cell Resolution Spanning Human Development and Maturation
12:05 PM - 12:20 PM EDT
Thursday, April 22, 2021Room: V100 - Ben Schramm Speaker
Grant Rowe, MD, PhD
Boston Children's Hospital
HSC Biology and Development
Short Talk: A Highly Multiplexed Single Cell Proteomic Screen Reveals the Phenotypic and Functional Landscape of the Human Lympho-Myeloid Differentiation Axis
12:20 PM - 12:35 PM EDT
Thursday, April 22, 2021Room: V100 - Ben Schramm Speaker
YeEun Kim, BS
Stanford
HSC Biology and Development
Short Talk: Definitive Hematopoietic Stem Cells Minimally Contribute to Embryonic Hematopoiesis
12:35 PM - 12:50 PM EDT
Thursday, April 22, 2021Room: V100 - Ben Schramm Speaker
Bianca Ulloa, MS
Albert Einstein College of Medicine
HSC Biology and Development
Short Talk: Selective Expansion of Human HSCs in Cytokine-Free Chemically-Defined Medium
12:50 PM - 1:05 PM EDT
Thursday, April 22, 2021Room: V100 - Ben Schramm Speaker
Hiromitsu Nakauchi
Stanford University
HSC Biology and Development
Meet the Editors Roundtable
2:30 PM - 3:30 PM EDT
Thursday, April 22, 2021Panelists
Daniel Klimmeck, PhD
EMBO Journal
Valerie Kouskoff, PhD
University of Manchester
Eric Sawey, PhD
Journal of Experimental Medicine (JEM)
Swapnika Ramu, PhD
Cell Press
Tanya Bondar, PhD
Blood Cancer Discovery of the American Association for Cancer Research
Keystone Symposia Roundtables
Hematologic Malignancies
5:00 PM - 8:00 PM EDT
Thursday, April 22, 2021Room: Multi-Room Split Session Co-Chairs
Daniel Starczynowski, PhD
Cincinnati Children's Hospital Medical Center
Ross Levine, MD
Memorial Sloan Kettering Cancer Center
Speakers
Michael Kharas, PhD
Memorial Sloan Kettering Cancer Center
Iannis Aifantis, PhD
New York University School of Medicine
Anna-Katharina Wirth, MS
Helmholtz Zentrum Munich
Jing Fang, MD, PhD
University of South Carolina
Amitava Sengupta, PhD
Indian Institute of Chemical Biology
Hematologic Malignancies
Adaptive Response of MDS Cells to the Inflammatory Milieu Contributes to Sustained Myeloid Expansion and a Competitive Advantage
5:00 PM - 5:25 PM EDT
Thursday, April 22, 2021Room: V100 - Ben Schramm Speaker
Daniel Starczynowski, PhD
Cincinnati Children's Hospital Medical Center
Hematologic Malignancies
RNA Binding Proteins in Leukemia
5:25 PM - 5:50 PM EDT
Thursday, April 22, 2021Room: V100 - Ben Schramm Speaker
Michael Kharas, PhD
Memorial Sloan Kettering Cancer Center
Hematologic Malignancies
RNA Binding Proteins as Regulators of Myeloid Leukemia Growth and Self-Renewal
5:50 PM - 6:15 PM EDT
Thursday, April 22, 2021Room: V100 - Ben Schramm Speaker
Iannis Aifantis, PhD
New York University School of Medicine
Hematologic Malignancies
Coffee Break
6:15 PM - 6:35 PM EDT
Thursday, April 22, 2021Hematologic Malignancies
Role of Mutations in Epigenetic Regulators in Clonal Hematopoiesis and Evolution to AML
6:35 PM - 7:00 PM EDT
Thursday, April 22, 2021Room: V200 - Ian Loudon Speaker
Ross Levine, MD
Memorial Sloan Kettering Cancer Center
Hematologic Malignancies
Short Talk: Modelling Acquired Treatment Resistance in PDX ALL in vivo Reveals Identical Therapeutic Targets Regardless of Diverse Genomic Alterations
7:00 PM - 7:15 PM EDT
Thursday, April 22, 2021Room: V200 - Ian Loudon Speaker
Anna-Katharina Wirth, MS
Helmholtz Zentrum Munich
Hematologic Malignancies
Short Talk: SF3B1 Mutations Induce Oncogenic IRAK4 Isoforms and Activate Targetable Innate Immune Pathways in MDS and AML
7:15 PM - 7:30 PM EDT
Thursday, April 22, 2021Room: V200 - Ian Loudon Speaker
Gaurav Choudhary, PhD
Albert Einstein College of Medicine
Hematologic Malignancies
Short Talk: Dissect the Function of GPR68 in Acute Myeloid Leukemia and Hematopoietic Stem Cells
7:30 PM - 7:45 PM EDT
Thursday, April 22, 2021Room: V200 - Ian Loudon Speaker
Jing Fang, MD, PhD
University of South Carolina
Hematologic Malignancies
Short Talk: Polybromo SWI/SNF Integrates Chromatin Remodeling & BMP/TGF-β Signaling to Determine Mesenchymal Stromal Osteolineage Commitment and Hematopoiesis
7:45 PM - 8:00 PM EDT
Thursday, April 22, 2021Room: V200 - Ian Loudon Speaker
Amitava Sengupta, PhD
Indian Institute of Chemical Biology
Hematologic Malignancies
Friday, April 23, 2021
Hematologic Malignancies: Biology and Therapy
10:00 AM - 1:00 PM EDT
Friday, April 23, 2021Room: Multi-Room Split Session Co-Chairs
Ravi Majeti, MD, PhD
Stanford University
Catriona Jamieson, MD, PhD
University of California, San Diego
Speakers
Kate Yen, PhD
Auron Therapeutics
Melvin Thomas III, PhD
St. Jude Children's Research Hospital
Panagiotis Ntziachristos, PhD
Northwestern University
Elvin Wagenblast, PhD
University Health Network, Princess Margaret Cancer Centre
Liping Li, MD, PhD
Johns Hopkins University
Shailaja Hegde, PhD
University of Cincinnati
Michael Lawler, MS
Thomas Jefferson University
Hematologic Malignancies: Biology and Therapy
Reprogramming B-ALL into APCs for Cancer Vaccination
10:00 AM - 10:25 AM EDT
Friday, April 23, 2021Room: V100 - Ben Schramm Speaker
Ravi Majeti, MD, PhD
Stanford University
Hematologic Malignancies: Biology and Therapy
Differentiation Therapy in AML
10:25 AM - 10:50 AM EDT
Friday, April 23, 2021Room: V100 - Ben Schramm Speaker
Kate Yen, PhD
Auron Therapeutics
Hematologic Malignancies: Biology and Therapy
Innate Immune Deaminases Fuel Pre-Leukemia Stem Cell Malignant Transformation
10:50 AM - 11:15 AM EDT
Friday, April 23, 2021Room: V100 - Ben Schramm Speaker
Catriona Jamieson, MD, PhD
University of California, San Diego
Hematologic Malignancies: Biology and Therapy
Coffee Break
11:15 AM - 11:30 AM EDT
Friday, April 23, 2021Hematologic Malignancies: Biology and Therapy
Short Talk: Germline Mutations in SAMD9 and SAMD9L Impair Hematopoietic Cell Function
11:30 AM - 11:45 AM EDT
Friday, April 23, 2021Room: V300 - Chad Littman Speaker
Melvin Thomas III, PhD
St. Jude Children's Research Hospital
Hematologic Malignancies: Biology and Therapy
Short Talk: Characterizing Mechanisms Controlling Aberrant Spliceosome Levels and Its Impact on Therapy Response in Acute Lymphoblastic Leukemia
11:45 AM - 12:00 PM EDT
Friday, April 23, 2021Room: V300 - Chad Littman Speaker
Panagiotis Ntziachristos, PhD
Northwestern University
Hematologic Malignancies: Biology and Therapy
Short Talk: Mapping the Cellular Origin and Developmental Context of Myeloid Leukemia in Down Syndrome
12:00 PM - 12:15 PM EDT
Friday, April 23, 2021Room: V300 - Chad Littman Speaker
Elvin Wagenblast, PhD
University Health Network, Princess Margaret Cancer Centre
Hematologic Malignancies: Biology and Therapy
Short Talk: High Mobility Group A1 Chromatin Remodeling Proteins Drive Progression in Myeloproliferative Neoplasms through Epigenetic Rewiring to Induce GATA2 and Cell Cycle Progression
12:15 PM - 12:30 PM EDT
Friday, April 23, 2021Room: V300 - Chad Littman Speaker
Liping Li, MD, PhD
Johns Hopkins University
Hematologic Malignancies: Biology and Therapy
Short Talk: Cell Basal Polarity Complex Scribble Is Required for Leukemic Initiation and Propagation through Negative Regulation of Apical Polarity Complex Activator Cdc42 and Hypoxia Inducing Factor-1α
12:30 PM - 12:45 PM EDT
Friday, April 23, 2021Room: V300 - Chad Littman Speaker
Shailaja Hegde, PhD
University of Cincinnati
Hematologic Malignancies: Biology and Therapy
Short Talk: Interrogation of TLR2 Inflammatory Signaling in AML
12:45 PM - 1:00 PM EDT
Friday, April 23, 2021Room: V300 - Chad Littman Speaker
Michael Lawler, MS
Thomas Jefferson University
Hematologic Malignancies: Biology and Therapy
Transcription and Epigenetics
5:00 PM - 8:00 PM EDT
Friday, April 23, 2021Room: Multi-Room Split Session Co-Chairs
Atsushi Iwama, MD, PhD
University of Tokyo
Margaret Goodell, PhD
Baylor College of Medicine
Speakers
Patricia Ernst, PhD
Professor, University of Colorado Anschutz Medical Center
Hanna Mikkola, MD, PhD
University of California, Los Angeles
Vikram Paralkar, MD
University of Pennsylvania
Maxim Pimkin, MD, PhD
Dana Farber Cancer Institute
Xiaotian Zhang, PhD
University of Michigan
Transcription and Epigenetics
Chromatin Accessibility in MDS Stem and Progenitor Cells
5:00 PM - 5:25 PM EDT
Friday, April 23, 2021Room: V200 - Ian Loudon Speaker
Atsushi Iwama, MD, PhD
University of Tokyo
Transcription and Epigenetics
MLL1 Levels and Activity Influence Hematopoietic Development
5:25 PM - 5:50 PM EDT
Friday, April 23, 2021Room: V200 - Ian Loudon Speaker
Patricia Ernst, PhD
Professor, University of Colorado Anschutz Medical Center
Transcription and Epigenetics
Mechanisms Regulating Human Hematopoietic Stem Cell Specification and Self-Renewal
5:50 PM - 6:15 PM EDT
Friday, April 23, 2021Room: V200 - Ian Loudon Speaker
Hanna Mikkola, MD, PhD
University of California, Los Angeles
Transcription and Epigenetics
Coffee Break
6:15 PM - 6:40 PM EDT
Friday, April 23, 2021Transcription and Epigenetics
Clonal Competition Among Hematopoietic Stem Cells
6:40 PM - 7:05 PM EDT
Friday, April 23, 2021Room: V300 - Chad Littman Speaker
Margaret Goodell, PhD
Baylor College of Medicine
Transcription and Epigenetics
Short Talk: An Atlas of Hematopoietic Transcription Factor Binding to Ribosomal DNA Reveals a Role for CEBPA in Regulation of rRNA Transcription
7:05 PM - 7:20 PM EDT
Friday, April 23, 2021Room: V300 - Chad Littman Speaker
Vikram Paralkar, MD
University of Pennsylvania
Transcription and Epigenetics
Short Talk: A Combinatorial Transcriptional Mechanism of Immune Escape in AML
7:20 PM - 7:35 PM EDT
Friday, April 23, 2021Room: V300 - Chad Littman Speaker
Maxim Pimkin, MD, PhD
Dana Farber Cancer Institute
Transcription and Epigenetics
Short Talk: 3D Genomics Analysis in Acute Myeloid Leukemia Reveals the Activation of the Homeobox Genes Driven Leukemic-Specific 3D Network
7:35 PM - 7:50 PM EDT
Friday, April 23, 2021Room: V300 - Chad Littman Speaker
Xiaotian Zhang, PhD
University of Michigan
Transcription and Epigenetics
Closing Remarks
7:50 PM - 8:00 PM EDT
Friday, April 23, 2021Room: V300 - Chad Littman Transcription and Epigenetics
