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Non-Coding RNAs: Biology and Applications

May 11-14, 2021 | 8:00AM EDT | 12:00PM UTC | 2:00PM CEST*
*Program is in development and subject to change


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Welcoming Remarks and Keynote Address
08:00am - 08:40am Eastern - May 11, 2021
David L. Spector, PhD, Organizer, Cold Spring Harbor Laboratory; Edith Heard, PhD, Keynote, European Molecular Biology Laboratory
Track: Welcoming Remarks and Keynote Address

Tuesday
The Multiple Roles of Xist RNA and It’s Partners during X-Chromosome Inactivation
08:00am - 08:40am Eastern - May 11, 2021
Edith Heard, PhD, European Molecular Biology Laboratory
Track: Welcoming Remarks and Keynote Address

Regulation of Long Noncoding RNA in Nuclear Condensates
08:40am - 10:25am Eastern - May 11, 2021
Sarah D. Diermeier, PhD, Co-Chair, University of Otago; Prasanth V. Kannanganattu, PhD, Co-Chair, University of Illinois
Track: Regulation of Long Noncoding RNA in Nuclear Condensates

Tuesday
The Elements and Machinery of Architectural Long Noncoding RNAs
08:40am - 09:05am Eastern - May 11, 2021
Tetsuro Hirose, PhD, Osaka University
Track: Regulation of Long Noncoding RNA in Nuclear Condensates

Tuesday
Repeat-Containing Noncoding RNAs in the Nucleolus
09:05am - 09:30am Eastern - May 11, 2021
Prasanth V. Kannanganattu, PhD, University of Illinois
Track: Regulation of Long Noncoding RNA in Nuclear Condensates

Tuesday
lncRNA SLERT Maintains Nucleolar Liquidity to Facilitate Pol I Transcription
09:30am - 09:55am Eastern - May 11, 2021
Ling-Ling Chen, PhD, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
Track: Regulation of Long Noncoding RNA in Nuclear Condensates

Tuesday
Short Talk: Control of Transcriptional Condensates and Gene Expression by Local Long Noncoding RNAs
09:55am - 10:10am Eastern - May 11, 2021
Jonathan E. Henninger, PhD, Whitehead Institute for Biomedical Research
Track: Regulation of Long Noncoding RNA in Nuclear Condensates

Tuesday
Short Talk: RNA Promotes the Formation of Spatial Compartments in the Nucleus
10:10am - 10:25am Eastern - May 11, 2021
Sofia Quinodoz, PhD, California Institute of Technology
Track: Regulation of Long Noncoding RNA in Nuclear Condensates

Noncoding RNA in Therapeutics
10:35am - 12:10pm Eastern - May 11, 2021
Sarah D. Diermeier, PhD, Co-Chair, University of Otago; Prasanth V. Kannanganattu, PhD, Co-Chair, University of Illinois
Track: Noncoding RNA in Therapeutics

Tuesday
Targeting Long Noncoding RNAs to Impact Breast Cancer Progression
10:35am - 11:00am Eastern - May 11, 2021
David L. Spector, PhD, Cold Spring Harbor Laboratory
Track: Noncoding RNA in Therapeutics

Tuesday
Mammary Tumor Associated RNAs as Drivers of Tumor Cell Growth and Metastasis
11:00am - 11:25am Eastern - May 11, 2021
Sarah D. Diermeier, PhD, University of Otago
Track: Noncoding RNA in Therapeutics

Tuesday
Short Talk: A Single N6-methyladenosine Site in lncRNA HOTAIR Regulates Its Function in Breast Cancer Cells
11:25am - 11:40am Eastern - May 11, 2021
Allison Marly Porman Swain, PhD, University of Colorado Anschutz Medical Campus
Track: Noncoding RNA in Therapeutics

Tuesday
Short Talk: LncRNA Malat1 Facilitates Breast Cancer Metastatic Dormancy and Reactivation by Immune Evasion
11:40am - 11:55am Eastern - May 11, 2021
Dhiraj Kumar, PhD, University of Texas MD Anderson Cancer Center
Track: Noncoding RNA in Therapeutics

Tuesday
Short Talk: LncRNA-Mediated Regulation of Vascular Senescence and Atherosclerosis
11:55am - 12:10pm Eastern - May 11, 2021
Mark W. Feinberg, MD, Brigham and Women’s Hospital/Harvard Medical School
Track: Noncoding RNA in Therapeutics

Tuesday
Career Roundtable
01:00pm - 02:00pm Eastern - May 11, 2021
Howard Y. Chang, MD, PhD, Panelist, Stanford University; Lynne E. Maquat, PhD, Panelist, University of Rochester Medical Center; Marco Marcia, PhD, Panelist, EMBL Grenoble
Track: Keystone Symposia Roundtables

Mechanisms of Long Noncoding RNA Function
08:00am - 10:00am Eastern - May 12, 2021
Jeremy E. Wilusz, PhD, Co-Chair, University of Pennsylvania; Xiaohua Shen, PhD, Co-Chair, Tsinghua University
Track: Mechanisms of Long Noncoding RNA Function

Wednesday
A Glimpse of ncRNA-mediated Transcription and Chromatin Regulation
08:00am - 08:25am Eastern - May 12, 2021
Xiaohua Shen, PhD, Tsinghua University
Track: Mechanisms of Long Noncoding RNA Function

Wednesday
Funations of Long Noncoding RNAs in Innate Immunity
08:25am - 08:50am Eastern - May 12, 2021
Xuetao Cao, MD, PhD, Nankai University and Chinese Academy of Medical Sciences
Track: Mechanisms of Long Noncoding RNA Function

Wednesday
Functions of Long Noncoding RNAs in Mammalian Cells
08:50am - 09:15am Eastern - May 12, 2021
Igor Ulitsky, PhD, Weizmann Institute of Science
Track: Mechanisms of Long Noncoding RNA Function

Wednesday
Short Talk: LncRNA NIHCOLE Promotes DNA Damage Repair of Hepatocellular Carcinoma Cells
09:15am - 09:30am Eastern - May 12, 2021
Juan Pablo Unfried, PhD, University of Navarra
Track: Mechanisms of Long Noncoding RNA Function

Wednesday
Short Talk: Systematic Discovery and Characterization of Cis-Regulatory Long Noncoding RNAs
09:30am - 09:45am Eastern - May 12, 2021
Rory Johnson, PhD, University College Dublin
Track: Mechanisms of Long Noncoding RNA Function

Wednesday
Short Talk: Structured Elements Drive Circular RNA Translation and Expand the Human Proteome
09:45am - 10:00am Eastern - May 12, 2021
Chun-Kan Chen, PhD, Stanford University School of Medicine
Track: Mechanisms of Long Noncoding RNA Function

Enhancer RNAs, Circular RNAs and Small RNA
10:25am - 11:35am Eastern - May 12, 2021
Jeremy E. Wilusz, PhD, Co-Chair, University of Pennsylvania; Xiaohua Shen, PhD, Co-Chair, Tsinghua University
Track: Enhancer RNAs, Circular RNAs and Small RNA

Wednesday
Harnessing Endonucleases to Control Gene Outputs
10:25am - 10:50am Eastern - May 12, 2021
Jeremy E. Wilusz, PhD, University of Pennsylvania
Track: Enhancer RNAs, Circular RNAs and Small RNA

Wednesday
Short Talk: Intergenerational Metabolic Priming by Sperm piRNAs
10:50am - 11:05am Eastern - May 12, 2021
Heidi Lempradl, PhD, Van Andel Institute
Track: Enhancer RNAs, Circular RNAs and Small RNA

Wednesday

Wednesday
Short Talk: An Essential Role for the piRNA Pathway in Regulating the Ribosomal RNA Pool in C. elegans
11:20am - 11:35am Eastern - May 12, 2021
Lamia Wahba, PhD, Stanford University
Track: Enhancer RNAs, Circular RNAs and Small RNA

Wednesday
Meet the Editors Roundtable
01:30pm - 02:30pm Eastern - May 12, 2021
Richard Hodge, Panelist, PLOS; Emily Marcinkevicius, PhD, Panelist, Cell Reports Methods; Di Jiang, Panelist, Science; Esther Schnapp, PhD, Panelist, EMBO Press; Elisa Zicola, PhD, Panelist, Frontiers Media SA
Track: Keystone Symposia Roundtables

RNA Structure and Function
08:00am - 09:55am Eastern - May 13, 2021
Lydia M. Contreras, PhD, Co-Chair, University of Texas at Austin; Matthew D. Simon, PhD, Co-Chair, Yale University
Track: RNA Structure and Function

Thursday
Structure Insights into Noncoding RNA Function
08:00am - 08:25am Eastern - May 13, 2021
Anna Marie Pyle, PhD, Yale University
Track: RNA Structure and Function

Thursday
Targeting Long Noncoding RNA with Small Molecules
08:25am - 08:50am Eastern - May 13, 2021
Amanda E. Hargrove, PhD, Duke University
Track: RNA Structure and Function

Thursday
Chemical Probing of RNA Structure in Cells
08:50am - 09:15am Eastern - May 13, 2021
Matthew D. Simon, PhD, Yale University
Track: RNA Structure and Function

Thursday
Structure-Functional Relationships in Long Non-Coding RNAs
09:15am - 09:40am Eastern - May 13, 2021
Marco Marcia, PhD, EMBL Grenoble
Track: RNA Structure and Function

Thursday
Short Talk: Linking MUNC lncRNA Structure with Its Function in Myogenesis
09:40am - 09:55am Eastern - May 13, 2021
Roza Kamila Przanowska, MS, University of Virginia
Track: RNA Structure and Function

RNA Technologies
10:15am - 12:00pm Eastern - May 13, 2021
Lydia M. Contreras, PhD, Co-Chair, University of Texas at Austin; Matthew D. Simon, PhD, Co-Chair, Yale University
Track: RNA Technologies

Thursday
Genome Regulation by Long Noncoding RNAs
10:15am - 10:40am Eastern - May 13, 2021
Howard Y. Chang, MD, PhD, Stanford University
Track: RNA Technologies

Thursday
Highly Efficient Expression of Circular RNAs in Cells using Autocatalytic Transcripts
10:40am - 11:05am Eastern - May 13, 2021
Samie Jaffrey, MD, PhD, Weill Medical College of Cornell University
Track: RNA Technologies

Thursday
Expanding Roles and Targeting of ncRNAs via Novel in vivo Characterization Approaches
11:05am - 11:30am Eastern - May 13, 2021
Lydia M. Contreras, PhD, University of Texas at Austin
Track: RNA Technologies

Thursday
Short Talk: PANDORA-seq Expands the Repertoire of Regulatory Small RNAs by Overcoming RNA Modifications
11:30am - 11:45am Eastern - May 13, 2021
Qi Chen, MD, PhD, University of California, Riverside
Track: RNA Technologies

Thursday
Short Talk: SPORTS1.1: A Tool for Annotating and Profiling Non-Coding RNAs Optimized for rRNA-and tRNA-Derived Small RNAs
11:45am - 12:00pm Eastern - May 13, 2021
Junchao Shi, MS, University of California, Riverside
Track: RNA Technologies

Noncoding RNA in Development and Disease
08:00am - 10:05am Eastern - May 14, 2021
Edward B. Chuong, PhD, Co-Chair, University of Colorado Boulder; Lin He, PhD, Co-Chair, University of California, Berkeley
Track: Noncoding RNA in Development and Disease

Friday
Noncoding RNAs in Post-Transcriptional Regulatory Circuits
08:00am - 08:25am Eastern - May 14, 2021
Joshua T. Mendell, MD, PhD, University of Texas Southwestern Medical Center
Track: Noncoding RNA in Development and Disease

Friday
Noncoding RNAs and Retrotransposons in Development
08:25am - 08:50am Eastern - May 14, 2021
Lin He, PhD, University of California, Berkeley
Track: Noncoding RNA in Development and Disease

Friday
IRENA Determines the Pro-Tumor and Anti-Tumor Properties of Inflammatory Macrophages
08:50am - 09:10am Eastern - May 14, 2021
Erwei Song, MD, PhD, Sun-Yat-Sen Memorial Hospital
Track: Noncoding RNA in Development and Disease

Friday
Long Noncoding RNA Regulation in Development
09:10am - 09:35am Eastern - May 14, 2021
John L. Rinn, PhD, University of Colorado Boulder
Track: Noncoding RNA in Development and Disease

Friday
Short Talk: Regulation of Cardiomyocyte Proliferation by LncRNA CARMN during Heart Regeneration in Zebrafish
09:35am - 09:50am Eastern - May 14, 2021
Mukesh Kumar Lalwani, PhD, University of Edinburgh
Track: Noncoding RNA in Development and Disease

Friday
Short Talk: Long Noncoding RNA Regulation in Human Fungal Pathogen Cryptococcus neoformans
09:50am - 10:05am Eastern - May 14, 2021
Murat Can Kalem, BS, University at Buffalo, State University of New York
Track: Noncoding RNA in Development and Disease