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Neuropsychiatric and Neurodevelopmental Disorders: Harnessing Rare Variants

February 11, 2021 | 10:00AM EST | 3:00PM UTC*
*Program is in development and subject to change



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The live portion of this conference has concluded and all presentations are now available for purchase on demand. Registrants to the live event may access this content anytime for up to 9 months following the event.


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This is an unprecedented time in psychiatric genetics. There are now hundreds of rare genetic variants that are strongly associated with neuropsychiatric traits and psychiatric diseases. Many individual teams are making progress studying a given gene or genomic interval, and the time is right for knowledge transfer across teams. This conference is driven by three emerging concepts. First, the discovery of rare variants with large effects for neuropsychiatric disorders provides a new avenue for understanding the underlying mechanisms of more common disorders. Second, these rare variants are often associated with multiple neurodevelopmental or neuropsychiatric disorders, suggesting that there are common underlying biological pathways that confer susceptibility to disease; this finding simultaneously suggests that genetic and epigenetic modifiers play a key role in determining the phenotype of specific individuals. Third, large scale collaborative efforts and harmonized frameworks for data collection are starting to enable more fine-grained, quantitative and even longitudinal phenotyping of probands and relatives, allowing us to move beyond the relatively gross characterization of categorical Diagnostic and Statistical Manual of Mental Disorders (DSM) diagnoses. These new findings underscore the need for interaction between geneticists, neurobiologists and clinical scientists, and this meeting sets the stage for such cross-cutting collaborations.

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Pricing:

Registration Rate: $150 USD

Deadlines:

Financial Aid Application: January 27, 2021

#VKSNeuroTreatment21


Financial Aid Opportunities

Graduate students and postdoctoral fellows, as well as individuals from low- and middle- income countries (all career stages) working in science and medicine-related fields, are eligible to apply for a FREE registration code.

Find out more about financial aid opportunities here!



Program Details



Keynote Speaker


Anthony Fauci, PhD

Anthony S. Fauci, MD
NIAID, National Institutes of Health



Speaking at this eSymposia


Wendy K. Chung

Columbia University, USA


John N. Constantino

Washington University School of Medicine, USA


Elise Robinson

Harvard T.H. Chan School of Public Health and Broad Institute, USA


Mustafa Sahin

Boston Children's Hospital, USA


Stephan Sanders

University of California, San Francisco


Jacob Vorstman

University of Toronto, USA



Program details will be available soon.


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Funding for this conference was made possible (in part) by Grant No. 1R13CA254450-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.




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#ScienceMustGoOn


This new virtual meeting format came out of difficult circumstances, but your commitment to scientific progress is what inspired us to launch Keystone eSymposia. In these virtual meetings, we are capturing the same innovative essence of our in-person meetings that you've all created as a scientific community. Here, Debbie Johnson, our CEO, explains how we're going to do that.







The views expressed in this eSymposia are those of the participants and not necessarily of the participants’ organizations or of Keystone Symposia.






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