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Joint meeting with Plant Genome Engineering: From Lab to Field

Precision Engineering of the Genome, Epigenome and Transcriptome

March 8-10, 2021 | 10:00AM EST | 3:00PM UTC | 4:00PM CET*
*Program is in development and subject to change



Joint Meetings

Your registration provides you with access to both the “Precision Engineering of the Genome, Epigenome and Transcriptome” and “Plant Genome Engineering: From Lab to Field” eSymposia events. Use the link below to explore the joint meeting features, including live plenary sessions, On Demand talks, posters, forums, job postings, 1:1 Connect appointments and more. This joint meeting access is designed to facilitate cross-disciplinary insights and collaborations to drive both fields in exciting new directions!

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Welcome and Keynote Address
10:00am - 10:40am Eastern - March 8, 2021
Fyodor D. Urnov, PhD, Chair, University of California, Berkeley; Tim W. Yu, MD, PhD, Keynote, Boston Children's Hospital
Track: Welcome and Keynote Address

Monday
Developing Custom Genetic Therapies
10:00am - 10:40am Eastern - March 8, 2021
Tim W. Yu, MD, PhD, Boston Children's Hospital
Track: Welcome and Keynote Address

Engineering of Editors and Epi-Editors
10:40am - 01:00pm Eastern - March 8, 2021
Samuel H. Sternberg, PhD, Co-Chair, Columbia University; Patrick D. Hsu, PhD, Co-Chair, University of California, Berkeley
Track: Engineering of Editors and Epi-Editors

Monday
Targeted DNA Integration using CRISPR RNA-Guided Transposases
10:40am - 11:05am Eastern - March 8, 2021
Samuel H. Sternberg, PhD, Columbia University
Track: Engineering of Editors and Epi-Editors

Monday
[NOT AVAILABLE ON DEMAND] New Editing Technologies
11:05am - 11:30am Eastern - March 8, 2021
Cecilia Cotta-Ramusino, PhD, Tessera Therapeutics
Track: Engineering of Editors and Epi-Editors

Monday
CRISPR in the Time of COVID
11:40am - 12:05pm Eastern - March 8, 2021
Patrick D. Hsu, PhD, University of California, Berkeley
Track: Engineering of Editors and Epi-Editors

Monday
[NOT AVAILABLE ON DEMAND] Endogenous RNA Editing Systems
12:05pm - 12:30pm Eastern - March 8, 2021
Prashant Mali, PhD, University of California, San Diego
Track: Engineering of Editors and Epi-Editors

Monday
Short Talk: A Compact Cascade-Cas3 System for Targeted Genome Engineering and Gene Discovery
12:30pm - 12:45pm Eastern - March 8, 2021
Track: Engineering of Editors and Epi-Editors

Monday
Short Talk: CRISPR-based Multimodal Functional Analysis Reveals the Key Role of Retroviral Sequence LTR7 in Governing Neural Fate Commitment of Human Embryo Development
12:45pm - 01:00pm Eastern - March 8, 2021
Yarui Diao, PhD, Duke University School of Medicine
Track: Engineering of Editors and Epi-Editors

Monday
[Joint Session] Career Roundtable
02:30pm - 03:30pm Eastern - March 8, 2021
Britt S. Adamson, PhD, Panelist, Princeton University; Rachel E. Haurwitz, PhD, Panelist, Caribou Biosciences, Inc.; Steven E. Jacobsen, PhD, Panelist, University of California, Los Angeles
Track: Career Roundtable

Controlling CRISPR
05:00pm - 08:00pm Eastern - March 8, 2021
Charles Gersbach, PhD, Co-Chair, Duke University; Henriette O'Geen, PhD, Co-Chair, University of California, Davis
Track: Controlling CRISPR

Monday
Visible and Invisible HDR in Human Cells
05:00pm - 05:25pm Eastern - March 8, 2021
Jacob E. Corn, PhD, ETH Zürich
Track: Controlling CRISPR

Monday
Multiplexed Probing of the Impact of Chromatin on Cas9-Induced DSB Repair Pathways
05:25pm - 05:50pm Eastern - March 8, 2021
Bas van Steensel, PhD, Netherlands Cancer Institute
Track: Controlling CRISPR

Monday
Design of Eukaryotic Gene Regulatory Circuits
05:50pm - 06:15pm Eastern - March 8, 2021
Ahmad S. Khalil, PhD, Boston University
Track: Controlling CRISPR

Monday
[NOT AVAILABLE ON DEMAND] Engineering the Repetitive 3D Genome in Human Disease
06:35pm - 07:00pm Eastern - March 8, 2021
Jennifer E. Phillips-Cremins, PhD, University of Pennsylvania
Track: Controlling CRISPR

Monday
Short Talk: Strategies to Improve Engineering Cancer Associated SNVs with Base Editing
07:00pm - 07:15pm Eastern - March 8, 2021
Alyna Yamuna Katti, BS, Weill Cornell Medicine
Track: Controlling CRISPR

Monday
Short Talk: Determinants of Persistence in Epigenetic Editing
07:30pm - 07:45pm Eastern - March 8, 2021
Henriette O'Geen, PhD, University of California, Davis
Track: Controlling CRISPR

Therapeutics I: Ex Vivo Editing
10:00am - 01:00pm Eastern - March 9, 2021
Rachel E. Haurwitz, PhD, Co-Chair, Caribou Biosciences, Inc.; Nicole Gaudelli, PhD, Co-Chair, Beam Therapeutics
Track: Therapeutics I: Ex Vivo Editing

Tuesday
The Future is Allogeneic - Translating a CRISPR Platform into Gene-Edited Cell Therapies
10:00am - 10:25am Eastern - March 9, 2021
Rachel E. Haurwitz, PhD, Caribou Biosciences, Inc.
Track: Therapeutics I: Ex Vivo Editing

Tuesday
Genome Editing of Blood Cells to Cure Disease
10:25am - 10:50am Eastern - March 9, 2021
Matthew Porteus, MD, PhD, Stanford University School of Medicine
Track: Therapeutics I: Ex Vivo Editing

Tuesday
T-Cell Gene Editing for Cancer Immunotherapy
10:50am - 11:15am Eastern - March 9, 2021
Chiara Bonini, MD, Vita-Salute San Raffaele University
Track: Therapeutics I: Ex Vivo Editing

Tuesday
An Adenine Base Editing Strategy for the Treatment of Sickle Cell Disease by Elimination of the Pathogenic Globin Protein
11:35am - 12:00pm Eastern - March 9, 2021
Nicole Gaudelli, PhD, Beam Therapeutics
Track: Therapeutics I: Ex Vivo Editing

Tuesday
[NOT AVAILABLE ON DEMAND] Short Talk: Knockout of NKG2A by CRISPR in Human NK Cells Enhance their Cytotoxic Activity Against Solid Tumors
12:00pm - 12:15pm Eastern - March 9, 2021
Delphine Guipouy, PhD, CHU Sainte Justine Research Center
Track: Therapeutics I: Ex Vivo Editing

Tuesday
Short Talk: Fast and Efficient Generation of TRAC-integrated CAR T Cells without Viruses
12:15pm - 12:30pm Eastern - March 9, 2021
Dimitrios Laurin Wagner, MD, Charité - Universitätsmedizin Berlin
Track: Therapeutics I: Ex Vivo Editing

Tuesday
Short Talk: Optimizing Stem Cell Lines for in vitro-derived Beta Cell Therapeutics via Genome-wide CRISPR Knock-out Screening
12:30pm - 12:45pm Eastern - March 9, 2021
Adrian Veres, PhD, Harvard University
Track: Therapeutics I: Ex Vivo Editing

Tuesday
Short Talk: Expanding the Scope of Marker-Free Selection for CRISPR-Driven Genome Editing in Human Cells
12:45pm - 01:00pm Eastern - March 9, 2021
Sébastien Levesque, MS, CHU de Québec - Université Laval
Track: Therapeutics I: Ex Vivo Editing

Tuesday
[Joint Session] Meet the Editors Roundtable
02:30pm - 03:30pm Eastern - March 9, 2021
Holger Breithaupt, PhD, Panelist, EMBO Press; Kevin Davies, Panelist, The CRISPR Journal; Bing Yang, Panelist, Frontiers in Genome Editing; Ruth Zearfoss, PhD, Panelist, Cell Reports Methods, Cell Press; Roland Roberts, PhD, Panelist, PLOS (Public Library of Science); Caitlin Karniski, PhD, Panelist, Nature Portfolio
Track: Meet the Editors Roundtable

Therapeutics II: In Vivo Editing
05:00pm - 07:45pm Eastern - March 9, 2021
Fyodor D. Urnov, PhD, Co-Chair, University of California, Berkeley; Ana Moreno Collado, PhD, Co-Chair, Navega Therapeutics
Track: Therapeutics II: In Vivo Editing

Tuesday
Development of crPhage to Treat Infections
05:00pm - 05:25pm Eastern - March 9, 2021
David G. Ousterout, PhD, Locus Biosciences, Inc.
Track: Therapeutics II: In Vivo Editing

Tuesday
Towards a CRISPRi/a Therapeutic for Radiation Injury
05:25pm - 05:50pm Eastern - March 9, 2021
Fyodor D. Urnov, PhD, University of California, Berkeley
Track: Therapeutics II: In Vivo Editing

Tuesday
Engineering AAV for Targeted In Vivo Editing
05:50pm - 06:15pm Eastern - March 9, 2021
Aravind Asokan, PhD, Duke University
Track: Delivery

Tuesday
Epigenome Regulation for Treatment of Chronic Pain
06:35pm - 07:00pm Eastern - March 9, 2021
Ana Moreno Collado, PhD, Navega Therapeutics
Track: Therapeutics II: In Vivo Editing

Tuesday
Short Talk: A Versatile Platform for ADAR-Mediated RNA Editing in vivo in Preclinical Models
07:00pm - 07:15pm Eastern - March 9, 2021
Chikdu Shivalila, PhD, Wave Life Sciences
Track: Therapeutics II: In Vivo Editing

Tuesday
Short Talk: Upregulation of Disease Compensatory Gene via CRISPR Activation in Muscular Dystrophy Mice
07:15pm - 07:30pm Eastern - March 9, 2021
Jia Qi Cheng-Zhang, MS, University of Pittsburgh
Track: Therapeutics II: In Vivo Editing

Tuesday
Short Talk: CRISPR Activation to Rescue SCN2A Haploinsufficiency in Autism Spectrum Disorder
07:30pm - 07:45pm Eastern - March 9, 2021
Serena Tamura, BA, University of California San Francisco
Track: Therapeutics II: In Vivo Editing

Delivery
10:00am - 12:50pm Eastern - March 10, 2021
Charles Gersbach, PhD, Co-Chair, Duke University; Daniel J. Siegwart, PhD, Co-Chair, University of Texas Southwestern Medical Center
Track: Delivery

Wednesday
Selective ORgan Targeting (SORT): A Synthetic Lipid Nanoparticle (LNP) Strategy for Effective Tissue-Specific Genome Engineering
10:00am - 10:25am Eastern - March 10, 2021
Daniel J. Siegwart, PhD, University of Texas Southwestern Medical Center
Track: Delivery

Wednesday
In Vivo Editing Approaches for Gene Therapy and Functional Genomics
10:25am - 10:50am Eastern - March 10, 2021
Charles Gersbach, PhD, Duke University
Track: Therapeutics II: In Vivo Editing

Wednesday
Delivering Gene Editing Components by Testing Thousands of Nanoparticles in vivo
10:50am - 11:15am Eastern - March 10, 2021
James Dahlman, PhD, Georgia Tech / Emory Medical School
Track: Delivery

Wednesday
Short Talk: Mesenchymal Stem Cell Delivery for Zinc Finger Proteins in Preclinical Animal Models of Angelman Syndrome
11:35am - 11:50am Eastern - March 10, 2021
Peter Deng, PhD, University of California, Davis
Track: Delivery

Wednesday

Wednesday

Wednesday
Short Talk: Controllable Genome Editing with Split-Engineered Base Editors
12:20pm - 12:35pm Eastern - March 10, 2021
Kiara Berrios, BS, University of Pennsylvania
Track: Delivery

Screening & Single Cell Technologies
05:00pm - 08:00pm Eastern - March 10, 2021
John G. Doench, PhD, Co-Chair, Broad Institute of MIT and Harvard University; Britt S. Adamson, PhD, Co-Chair, Princeton University
Track: Screening & Single Cell Technologies

Wednesday
Bridging the Variant-to-Function Chasm: Screens with Base Editor Technology
05:00pm - 05:25pm Eastern - March 10, 2021
John G. Doench, PhD, Broad Institute of MIT and Harvard University
Track: Screening & Single Cell Technologies

Wednesday
Single Cell Sequencing Technologies
05:25pm - 05:50pm Eastern - March 10, 2021
Britt S. Adamson, PhD, Princeton University
Track: Screening & Single Cell Technologies

Wednesday
Predicting the Efficiencies and Outcomes of Genome Editing using Deep Learning
05:50pm - 06:15pm Eastern - March 10, 2021
Hyongbum Henry Kim, MD, PhD, Yonsei University College of Medicine
Track: Screening & Single Cell Technologies

Wednesday
Genome-Wide Programmable Transcriptional Memory by CRISPR-Based Epigenome Editing
06:30pm - 06:55pm Eastern - March 10, 2021
Jonathan S. Weissman, PhD, Whitehead Institute and MIT
Track: Screening & Single Cell Technologies

Wednesday
Short Talk: Functional Interrogation of DNA Damage Response Variants with Base Editing Screens
06:55pm - 07:10pm Eastern - March 10, 2021
Alberto Ciccia, PhD, Columbia University
Track: Screening & Single Cell Technologies

Wednesday
Short Talk: Harnessing Epigenetic Editing Tools to Identify and Modulate Mechanically-Activated Genomic Enhancers
07:10pm - 07:25pm Eastern - March 10, 2021
Brian Cosgrove, PhD, Duke University
Track: Screening & Single Cell Technologies

Wednesday
[NOT AVAILABLE ON DEMAND] Short Talk: Toward Genome-Scale Single-Cell Screens with Multi-Modal Perturb-Seq
07:25pm - 07:40pm Eastern - March 10, 2021
Pratiksha Thakore, PhD, Broad Institute
Track: Screening & Single Cell Technologies

Wednesday
Short Talk: Spear-ATAC: Pooled, Droplet-Based, Single-Cell Chromatin Accessibility CRISPR Screens
07:40pm - 07:55pm Eastern - March 10, 2021
Sarah Elisabeth Pierce, BS, Stanford University
Track: Screening & Single Cell Technologies

Wednesday
Closing Remarks
07:55pm - 08:00pm Eastern - March 10, 2021
Track: Screening & Single Cell Technologies