Joint meeting with NeuroImmune Interactions in Health and Disease
Neurodegenerative Diseases: Genes, Mechanisms and Therapeutics
June 7-9, 2021 | 9:00AM EDT | 1:00PM UTC | 3:00PM CEST*
*Program is in development and subject to change
Joint Meetings
Your registration provides you with access to both the “Neurodegenerative Diseases: Genes, Mechanisms and Therapeutics” and “NeuroImmune Interactions in Health and Disease” eSymposia events. Use the link below to explore the joint meeting features, including live plenary sessions, On Demand talks, posters, forums, job postings, 1:1 Connect appointments and more. This joint meeting access is designed to facilitate cross-disciplinary insights and collaborations to drive both fields in exciting new directions!
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Showing results 1 - 10 of 11
Monday, June 7, 2021
[Joint Session] Welcoming Remarks and Keynote Address
9:00 AM - 10:10 AM EDT
Monday, June 7, 2021Co-Chairs
Eric Huang, MD, PhD
University of California, San Francisco
Beth Stevens, PhD
Boston Children's Hospital, Harvard Medical School
[Joint Session] Welcoming Remarks and Keynote Address
Manipulating Immune Trafficking In and Out of the CNS
9:00 AM - 9:40 AM EDT
Monday, June 7, 2021Speaker
Akiko Iwasaki, PhD
Yale University School of Medicine
[Joint Session] Welcoming Remarks and Keynote Address
Exploiting Dynamic Enhancer Landscapes to Infer Pathogenic Mechanisms in Neurodegenerative Diseases
9:40 AM - 10:10 AM EDT
Monday, June 7, 2021Speaker
Christopher Glass, MD, PhD
University of California, San Diego
[Joint Session] Welcoming Remarks and Keynote Address
[Joint Session] Disease Mechanisms and Therapeutic Targets
10:10 AM - 1:00 PM EDT
Monday, June 7, 2021Co-Chairs
Joseph Lewcock, PhD
Denali Therapeutics
Kate Monroe, PhD
Denali Therapeutics
[Joint Session] Disease Mechanisms and Therapeutic Targets
Antisense Oligonucleotides for the Treatment of Neurological Diseases
10:10 AM - 10:35 AM EDT
Monday, June 7, 2021Room: V300 - Ian Speaker
Holly Kordasiewicz, PhD
Ionis Pharmaceuticals
[Joint Session] Disease Mechanisms and Therapeutic Targets
Therapeutic Strategies for the Treatment of Neurodegenerative Disease Based on Human Genetics
10:35 AM - 11:00 AM EDT
Monday, June 7, 2021Room: V300 - Ian Speaker
Joseph Lewcock, PhD
Denali Therapeutics
[Joint Session] Disease Mechanisms and Therapeutic Targets
Enhancing Microglia Function with ATV:TREM2
11:00 AM - 11:25 AM EDT
Monday, June 7, 2021Room: V300 - Ian Speaker
Kate Monroe, PhD
Denali Therapeutics
[Joint Session] Disease Mechanisms and Therapeutic Targets
Coffee Break
11:25 AM - 11:50 AM EDT
Monday, June 7, 2021[Joint Session] Disease Mechanisms and Therapeutic Targets
Neuroimmunological Target Considerations - To Be or Not To Be in the Brain
11:50 AM - 12:15 PM EDT
Monday, June 7, 2021Speaker
Johan Luthman, PhD
Lundbeck
[Joint Session] Disease Mechanisms and Therapeutic Targets
Short Talk: TREM2-Independent Neuroprotection Mediated by Monocyte-Derived Macrophages in a Mouse Model of Alzheimer’s Disease
12:15 PM - 12:30 PM EDT
Monday, June 7, 2021Speaker
Raz Dvir Szternfeld, MS
Weizmann Institute of Science
[Joint Session] Disease Mechanisms and Therapeutic Targets
Short Talk: Myokine Irisin Is a Critical Regulator of Cognitive Function
12:30 PM - 12:45 PM EDT
Monday, June 7, 2021Speaker
Christiane Wrann, PhD
Massachusetts General Hospital
[Joint Session] Disease Mechanisms and Therapeutic Targets
Short Talk: Highly Conserved Glial Pathology and Human-Specific Neuronal Pathology Promote Neurodegeneration in FTLD-GRN
12:45 PM - 1:00 PM EDT
Monday, June 7, 2021Speaker
Elise Marsan, PhD
University of California, San Francisco
[Joint Session] Disease Mechanisms and Therapeutic Targets
From Therapeutic Targets to Clinic
1:00 PM - 2:30 PM EDT
Monday, June 7, 2021Co-Chairs
Joseph Lewcock, PhD
Denali Therapeutics
Charlotte Sumner, MD
Johns Hopkins School of Medicine
From Therapeutic Targets to Clinic
The Evolving Challenges of Gene Targeted Therapeutics for SMA
1:00 PM - 1:25 PM EDT
Monday, June 7, 2021Speaker
Charlotte Sumner, MD
Johns Hopkins School of Medicine
From Therapeutic Targets to Clinic
Engineering Gene-Based Medicines for the Brain
1:25 PM - 1:50 PM EDT
Monday, June 7, 2021Speaker
Beverly Davidson, PhD
Children’s Hospital of Philadelphia and University of Pennsylvania
From Therapeutic Targets to Clinic
IPSC-Derived Dopaminergic Neurons and Parkinson's Disease Therapy
1:50 PM - 2:15 PM EDT
Monday, June 7, 2021Speaker
Lorenz Studer, MD
Memorial Sloan Kettering Cancer Center
From Therapeutic Targets to Clinic
Short Talk: Discovering and Reversing the Metabolic Consequences of APOE4 in iPSC-Derived Glia
2:15 PM - 2:30 PM EDT
Monday, June 7, 2021Speaker
Priyanka Narayan, PhD
National Institute of Health
From Therapeutic Targets to Clinic
Tuesday, June 8, 2021
Genetic Contributions to Neurodegeneration
9:00 AM - 10:20 AM EDT
Tuesday, June 8, 2021Co-Chairs
Valina Dawson, PhD
Johns Hopkins University School of Medicine
Alison Goate, PhD
Icahn School of Medicine at Mount Sinai
Genetic Contributions to Neurodegeneration
Human Genetics Implicates Microglial Function in Alzheimer’s Disease Risk
9:00 AM - 9:25 AM EDT
Tuesday, June 8, 2021Room: V300 - Ian Speaker
Alison Goate, PhD
Icahn School of Medicine at Mount Sinai
Genetic Contributions to Neurodegeneration
Immune Contributions to Early-Onset Neurodegenerative Disease
9:25 AM - 9:50 AM EDT
Tuesday, June 8, 2021Room: V300 - Ian Speaker
Jennifer Yokoyama, PhD
University of California, San Francisco
Genetic Contributions to Neurodegeneration
Short Talk: Modeling the Impact of AD Genetic Risk on Microglia States and Function
9:50 AM - 10:05 AM EDT
Tuesday, June 8, 2021Room: V300 - Ian Speaker
Martine Therrien, PhD
Broad Institute
Genetic Contributions to Neurodegeneration
Short Talk: Impact of PLCG2 Alzheimer's Disease Risk Variants on Microglia Biology and Disease Pathogenesis
10:05 AM - 10:20 AM EDT
Tuesday, June 8, 2021Room: V300 - Ian Speaker
Andy Po-Yi Tsai, MS
Indiana University School of Medicine
Genetic Contributions to Neurodegeneration
Cellular Pathways Targeted by Neurodegeneration
10:20 AM - 11:30 AM EDT
Tuesday, June 8, 2021Co-Chairs
Alison Goate, PhD
Icahn School of Medicine at Mount Sinai
Valina Dawson, PhD
Johns Hopkins University School of Medicine
Cellular Pathways Targeted by Neurodegeneration
Mechanism of A-Synuclein-Mediated Neurodegeneration
10:20 AM - 10:45 AM EDT
Tuesday, June 8, 2021Speaker
Valina Dawson, PhD
Johns Hopkins University School of Medicine
Cellular Pathways Targeted by Neurodegeneration
Short Talk: Synapsin and Synaptic Vesicle Condensates Recruit alpha-Synuclein
10:45 AM - 11:00 AM EDT
Tuesday, June 8, 2021Speaker
Christian Hoffmann, PhD
German Center for Neurodegenerative Diseases - DZNE
Cellular Pathways Targeted by Neurodegeneration
Short Talk: Cerebellar Degeneration in ARSACS Disease Linked to Tau Hyperphosphorylation and Membrane-Protein Disruption
11:00 AM - 11:15 AM EDT
Tuesday, June 8, 2021Speaker
Kathryn Hixson, PhD
UNC Chapel Hill
Cellular Pathways Targeted by Neurodegeneration
Short Talk: Identification of Small Molecule Drugs that Target Apolipoprotein E4-Catalyzed Amyloid-β Fibrillization: A New Therapeutic Approach to Alzheimer’s Disease
11:15 AM - 11:30 AM EDT
Tuesday, June 8, 2021Speaker
Noah Johnson, PhD
University of Colorado Anschutz Medical Campus
Cellular Pathways Targeted by Neurodegeneration
Glial Contributions to Neurodegeneration
12:05 PM - 2:25 PM EDT
Tuesday, June 8, 2021Co-Chairs
Michael Heneka, MD
German Center for Neurodegenerative Diseases
Mathew Blurton-Jones, PhD
University of California, Irvine
Glial Contributions to Neurodegeneration
Novel Genetic Tools for Studying Myeloid Cells in the CNS
12:05 PM - 12:25 PM EDT
Tuesday, June 8, 2021Room: V300 - Ian Speaker
Marco Prinz, MD
University of Freiburg
Glial Contributions to Neurodegeneration
Microglia Shape Neuronal and Vascular Responses via Compartment-Specific Purinergic Mechanisms
12:25 PM - 12:50 PM EDT
Tuesday, June 8, 2021Room: V300 - Ian Speaker
Ádám Dénes, PhD
Hungarian Academy of Sciences
Glial Contributions to Neurodegeneration
Control of Neuron Activity by Microglia
12:50 PM - 1:15 PM EDT
Tuesday, June 8, 2021Room: V300 - Ian Speaker
Anne Schaefer, MD, PhD
Mount Sinai School of Medicine
Glial Contributions to Neurodegeneration
Inflammasome Activation in Alzheimer's Disease
1:15 PM - 1:40 PM EDT
Tuesday, June 8, 2021Room: V300 - Ian Speaker
Michael Heneka, MD
German Center for Neurodegenerative Diseases
Glial Contributions to Neurodegeneration
Short Talk: Depletion of AD Risk Gene Sortilin-Related Receptor (SORL1) Causes Cell-Type Specific Dysfunction of the Endo-Lysosomal Pathway in Human Neurons and Microglia – Implications in Alzheimer’s Disease (AD)
1:40 PM - 1:55 PM EDT
Tuesday, June 8, 2021Room: V300 - Ian Speaker
Swati Mishra, PhD
University of Washington
Glial Contributions to Neurodegeneration
Short Talk: Astrocytic BMAL1 Regulates Protein Aggregation in Mouse Models of Alpha-Synuclein and Tau Pathology
1:55 PM - 2:10 PM EDT
Tuesday, June 8, 2021Room: V300 - Ian Speaker
Patrick Sheehan, BS
Washington University in St. Louis
Glial Contributions to Neurodegeneration
Short Talk: Loss of NPC1 Enhances Phagocytic Uptake and Impairs Lipid Trafficking in Microglia
2:10 PM - 2:25 PM EDT
Tuesday, June 8, 2021Room: V300 - Ian Speaker
Sabina Tahirovic, PhD
Deutsches Zentrum für Neurodegenerative Erkrankungen e. V. - DZNE
Glial Contributions to Neurodegeneration
[Joint Session] Meet the Editors Roundtable
3:30 PM - 4:30 PM EDT
Tuesday, June 8, 2021Speakers
Swapnika Ramu, PhD
Cell Press
Gabriel Gasque, PhD
PLOS (Public Library of Science)
Sophie Morgan, PhD
Nature Communications
Tim Spencer, PhD
Journal of Cell Biology (JCB)
Keystone Symposia Roundtables
Wednesday, June 9, 2021
Phase Separation, Protein Aggregation and Transmission
9:00 AM - 10:45 AM EDT
Wednesday, June 9, 2021Co-Chairs
Eric Huang, MD, PhD
University of California, San Francisco
Virginia Lee, PhD
University of Pennsylvania School of Medicine
Phase Separation, Protein Aggregation and Transmission
Phase Separation of RNA Binding Proteins in Neurodegeneration
9:00 AM - 9:25 AM EDT
Wednesday, June 9, 2021Room: V300 - Ian Speaker
J. Paul Taylor, MD, PhD
St. Jude Children's Research Hospital
Phase Separation, Protein Aggregation and Transmission
Cryo-EM Structures of Amyloid Filaments from Human Brain
9:25 AM - 9:50 AM EDT
Wednesday, June 9, 2021Room: V300 - Ian Speaker
Sjors Scheres, PhD
MRC Laboratory of Molecular Biology
Phase Separation, Protein Aggregation and Transmission
Tau and A-Synuclein Aggregation and Spreading
9:50 AM - 10:15 AM EDT
Wednesday, June 9, 2021Room: V300 - Ian Speaker
Virginia Lee, PhD
University of Pennsylvania School of Medicine
Phase Separation, Protein Aggregation and Transmission
Short Talk: Nuclear Accumulation of CHMP7 Initiates Nuclear Pore Complex Injury and Subsequent TDP-43 Dysfunction in Sporadic and Familial ALS
10:15 AM - 10:30 AM EDT
Wednesday, June 9, 2021Room: V300 - Ian Speaker
Alyssa Coyne, PhD
Johns Hopkins University School of Medicine
Phase Separation, Protein Aggregation and Transmission
Short Talk: Role of RAB7A Mutations in Charcot-Marie-Tooth Type 2B Disease
10:30 AM - 10:45 AM EDT
Wednesday, June 9, 2021Room: V300 - Ian Speaker
Roberta Romano, PhD
University of Salento
Phase Separation, Protein Aggregation and Transmission
Epigenetics and Transcriptomics of the Aging Brain
10:45 AM - 1:00 PM EDT
Wednesday, June 9, 2021Co-Chairs
Li-Huei Tsai, PhD
Massachusetts Institute of Technology
Richard Ransohoff, MD
Harvard Medical School
Epigenetics and Transcriptomics of the Aging Brain
Transcriptomic Dissection of Alzheimer’s Disease at the Single Cell Resolution
10:45 AM - 11:10 AM EDT
Wednesday, June 9, 2021Speaker
Li-Huei Tsai, PhD
Massachusetts Institute of Technology
Epigenetics and Transcriptomics of the Aging Brain
Epigenetics and Systems Biology of Alzheimer's Disease
11:10 AM - 11:35 AM EDT
Wednesday, June 9, 2021Speaker
Philip De Jager, MD, PhD
Columbia University Medical Center
Epigenetics and Transcriptomics of the Aging Brain
Coffee Break
11:35 AM - 12:05 PM EDT
Wednesday, June 9, 2021Epigenetics and Transcriptomics of the Aging Brain
Neuro-Immune Interactions in the Aging Neurogenic Niche
12:05 PM - 12:30 PM EDT
Wednesday, June 9, 2021Speaker
Anne Brunet, PhD
Stanford University
Epigenetics and Transcriptomics of the Aging Brain
Short Talk: Multi-Tissue High-Throughput Proteomics Profiling for Neurodegenerative Disease
12:30 PM - 12:45 PM EDT
Wednesday, June 9, 2021Speaker
Carlos Cruchaga, PhD
Washington University School of Medicine
Epigenetics and Transcriptomics of the Aging Brain
Short Talk: Transposable Element Insertions Associated with Risk of Neurologic and Psychiatric Diseases
12:45 PM - 1:00 PM EDT
Wednesday, June 9, 2021Speaker
Hyo Won Ahn, MS
National Institute of Child Health and Human Development
Epigenetics and Transcriptomics of the Aging Brain
Modeling Neuro-Immune Interactions in Neurodegeneration
1:00 PM - 2:40 PM EDT
Wednesday, June 9, 2021Co-Chairs
Li-Huei Tsai, PhD
Massachusetts Institute of Technology
Mathew Blurton-Jones, PhD
University of California, Irvine
Modeling Neuro-Immune Interactions in Neurodegeneration
Cerebral Organoids and Neurodegeneration
1:00 PM - 1:25 PM EDT
Wednesday, June 9, 2021Room: V300 - Ian Speaker
Fred Gage, PhD
The Salk Institute for Biological Studies
Modeling Neuro-Immune Interactions in Neurodegeneration
Multiple Sclerosis Neurorepair – A Drug Discovery Perspective
1:25 PM - 1:50 PM EDT
Wednesday, June 9, 2021Room: V300 - Ian Speaker
Hui-Hsin Tsai, PhD
Biogen
Modeling Neuro-Immune Interactions in Neurodegeneration
Neuro-Immune Interactions in AD Models
1:50 PM - 2:15 PM EDT
Wednesday, June 9, 2021Room: V300 - Ian Speaker
Mathew Blurton-Jones, PhD
University of California, Irvine
Modeling Neuro-Immune Interactions in Neurodegeneration
Short Talk: CRISPRi-based Genetic Screens in iPSC-Derived 3D Neuron-Astrocyte-Microglia iAssembloids
2:15 PM - 2:30 PM EDT
Wednesday, June 9, 2021Room: V300 - Ian Speaker
Emmy Li, BS
University of California, San Francisco
Modeling Neuro-Immune Interactions in Neurodegeneration
Closing Remarks
2:30 PM - 2:40 PM EDT
Wednesday, June 9, 2021Room: V300 - Ian Modeling Neuro-Immune Interactions in Neurodegeneration
