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Autophagy: Mechanisms and Disease

October 5-8, 2020 | 8:00AM EDT | 12:00PM UTC*
*Program is in development and subject to change

Autophagy is an intracellular pathway for degradation that allows for the recycling of cellular components inside lysosomes to sustain tissue homeostasis. Countless effort has been devoted to help unravel the molecular mechanisms that regulate this pathway, but many questions remain unresolved. Therefore, this conference program gathers an interdisciplinary group of scientists to address the current and future challenges in the field such as discussions on the existence of non-canonical forms of the pathway and how selectivity is achieved. This conference also addresses the minimal requirements to generate functional autophagosomes and the molecular bases of autophagy regulation. One of the major themes of this conference is a session which reviews how model systems such as plants, worms and mice help to unravel the physiological roles of this essential pathway and why this research can also be applied to find new therapies for human diseases. For example, while it is now clear that many human pathologies have alterations in autophagy, how scientists could potentially manipulate the pathway in vivo is a major challenge that will be addressed at this conference. Finally, this conference provides a unique frame to display the current research and future challenges of the field during physiological and pathological conditions.

Program is intended for scientific researchers and clinical audiences.

Join us for this landmark virtual event, brought to you by Keystone Symposia.


Registration for this meeting is now closed.


ePoster Abstract Submission: Passed
Financial Aid Application: Passed


Program Details

Speaking at this eSymposia

Eric H. Baehrecke

University of Massachusetts Medical School, USA

Patricia Boya

Centro de Investigaciones Biológicas, CSIC, Spain

Ana Maria Cuervo

Albert Einstein College of Medicine, USA

Ivan Dikic

Goethe University Medical School, Germany

Martin Graef

Max Planck Institute for Biology of Aging, Germany

Masaaki Komatsu

Juntendo University School of Medicine, Japan

Guido Kroemer

Cordeliers Research Center, France

Jennifer Martinez

NIEHS, National Institutes of Health, USA

Martin McMahon

University of Utah School of Medicine, USA

Alicia Melendez

Queens College - CUNY, USA

Noboru Mizushima

University of Tokyo, Japan

Leon O. Murphy

Casma Therapeutics, USA

Tassula Proikas-Cezanne

University of Tuebingen, Germany

Rosa Puertollano

NHLBI, National Institutes of Health, USA

Felix Randow

Medical Research Council, UK

Fulvio Reggiori

University Medical Centre Groningen, Netherlands

David C. Rubinsztein

Cambridge Institute for Medical Research, UK

Katja Simon

University of Oxford, UK

Anne Simonsen

University of Oslo, Norway

Herbert (Skip) W. Virgin

Vir Biotechnology, USA

Richard J. Youle

NINDS, National Institutes of Health, USA

Hong Zhang

Chinese Academy of Sciences, China

The views expressed in this eSymposia are those of the participants and not necessarily of the participants’ organizations or of Keystone Symposia.

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