Error loading player: No playable sources found

  To view this video content in its entirety, click on the "Access Content" button and login to your account.

If you do not have an account, register for free.

Please note that the account you create here is different than your Keystone Symposia account at www.keystonesymposia.org used to register for our multi-day conferences and is uniquely for viewing our virtual content.


Role of the Genital Tract Microbiome in Sexual and Reproductive Health

Date
December 3, 2019
Free
Standard Price
This product is also available as part of the following products:


Bacteria and fungi residing in the female genital tract have been associated with elevated risks of HIV acquisition and transmission, pelvic inflammatory disease, miscarriage, preterm birth, and invasive maternal and neonatal infections. The increased availability of high-throughput genomic testing since the turn of the century has revealed a more detailed picture of these organisms than was possible when evaluation depended on microscopy and culture. The interrelationships between sexually transmitted infections, vaginal dysbiosis, vulvovaginal candidiasis, and vaginal pathobiont carriage are being elucidated, and their effects on the cervicovaginal mucosal barrier and immune system are being characterized. The mechanisms that may lead to adverse outcomes are being unraveled, and an increasing number of interventions are in clinical trials.

This thought-provoking epanel broadcast will discuss a range of questions and challenges surrounding the role of genital tract microbiome in sexual and reproductive health, including:

  • What is our current understanding of female and male genital tract microbiology and immunology?
  • What are the areas of consensus and which areas require further research?
  • How does dysbiosis develop and resolve?
  • What is the role of mucosal biofilms?
  • What is the role of dysbiosis in HIV acquisition and transmission, pregnancy complications, and other adverse outcomes?
  • How can we translate this new knowledge into diagnostic testing, prevention and treatment strategies?

Following the panel discussion broadcast, audience members watching the live event will be able to participate in a live Q&A with the panelists. Questions can be submitted during the broadcast via Twitter or the chat room, or in advance when registering for the event.

This ePanel was filmed during the Keystone Symposia conference on Role of the Genital Tract Microbiome in Sexual and Reproductive Health at the Southern Sun Cape Sun, Cape Town, Western Cape South Africa, December 11—15, 2018, and was made possible with funding from The Bill and Melinda Gates Foundation.



Hashtag: #VKSgentract





Video Previews



Moderator

Speaker Image for Janneke van de Wijgert
University Medical Center Utrecht

Speakers

Speaker Image for Jo-Ann  Passmore
University of Cape Town
Speaker Image for Doug Kwon
Doug Kwon, MD, PhD
Harvard Medical School
Speaker Image for Jeanne Marrazzo
University of Alabama at Birmingham
Speaker Image for Caroline Cameron
University of Victoria

Related Products

Thumbnail for Role of Lactobacillus iners in the Vaginal Microbiota
Role of Lactobacillus iners in the Vaginal Microbiota
The vaginal microbial community is typically characterized by abundant lactobacilli. Lactobacillus iners, a fairly recently detected species, is frequently present in the vaginal niche…
Thumbnail for Exploring microbe-immune crosstalk: immunoglobulin coating of vaginal microbiota
Exploring microbe-immune crosstalk: immunoglobulin coating of vaginal microbiota
Heleen Schuster MDa,b, Annelot Breedveld MScc, Andries Budding MD PhDa, Paul Savelkoul PhDa,d
Thumbnail for The Malaria Endgame
The Malaria Endgame
This ePanel, filmed during the Keystone Symposia Conference: The Malaria Endgame: Innovation in Therapeutics, Vector Control and Public Health Tools [https://tks.keystonesymposia.org/index.cfm?e=web.Meeting…
Thumbnail for Autophagy: From Model Systems to Therapeutic Opportunities
Autophagy: From Model Systems to Therapeutic Opportunities
Autophagy is a homeostatic process strategically positioned at the intersection of metabolism and intracellular quality control, with broad physiological and medical manifestations ranging from metabolic imbalance to neurodegeneration, infections, immune disorders, cancer and aging…