Virtual Access: Mitochondrial Biology & Selective Autophagy

Organizers: Jodi Nunnari, Anu Suomalainen-Wartiovaara, Koji Okamoto, Tamotsu Yoshimori, Hong Zhang and Anne Simonsen

Mitochondrial dysfunction has emerged as a key factor in a myriad of diseases, including neurodegenerative and metabolic disorders. Likewise, several diseases have been linked to dysfunctional selective autophagy. Protein aggregates and damaged or superfluous organelles such as mitochondria, ER, peroxisomes, endosomes and lysosomes can be degraded by autophagy in a highly selective manner that plays a key role in cellular homeostasis. The aims of the joint Keystone Symposia conferences on "Mitochondrial Biology" and "Selective Autophagy" were to:

  • Explore the most up-to-date progress regarding the molecular mechanisms underlying selective autophagy and its link with multiple diseases, including presentations on the autophagic machinery that mediates removal of different types of cargo and dysregulated selective autophagy in diseases, including neurodegenerative and immune diseases;
  • Present and discuss cutting-edge results regarding how mitochondrial form and function are controlled at the cellular and organismal levels and how the many functions of mitochondria impinge on health and disease states, including cancer;
  • Discuss how new technologies and experimental approaches, such as imaging, will speed progress in the two fields;
  • Provide a forum for trainees and junior investigators to learn about current progress and future directions of the field, and to establish discussions and networks with other investigators;
  • Stimulate collaborations among scientists in each field, and across the two fields.

To view the program of this conference, visit and

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Keystone Symposia convenes dynamic, open, peer-reviewed conferences on the exciting new frontiers of life science. Whether you are a geneticist, an immunologist or virtually any other type of life science investigator, and whether you are from academia, industry or the government/nonprofit sector, we think you will find the experience of attending a Keystone Symposia meeting valuable and memorable.

Keystone Symposia on Molecular and Cellular Biology is a 501(c)(3) nonprofit organization with a 45-year history of convening open, peer-reviewed conferences that connect the scientific community and accelerate life science discovery.

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