Roughly 2,000 years ago, the Roman Celsus first recorded the cardinal signs of inflammation as “calor” (warmth), “dolor” (pain), “tumor” (swelling), and “rubor” (redness) in his work De Medicina. Today, our understanding of inflammation has moved considerably beyond its outward manifestations. Inflammation is a complex multi-systemic process that is necessary for key mechanisms such as fighting infection and wound healing, but it also causes or contributes to many debilitating conditions.
Download this poster from The Scientist's Creative Services Division to learn more about how inflammation both fights against and aids in the genesis of disease!