Cancer cells survive by manipulating direct interactions with other cells, but they thrive by changing the environment they live in. This tumor microenvironment (TME) favors cancer cell survival and protects against antagonists, making it a major obstacle for many potential therapeutic approaches. A greater understanding of the TME will enable scientists to manipulate it to create an environment more amenable to anticancer strategies.
Download this poster from The Scientist's Creative Services team to learn about how scientists are targeting angiogenesis, metabolic reprogramming, and immune evasion mechanisms to overcome the TME.