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Lipidomics of Health and Disease

March 24-26, 2021 | 10:00AM EDT | 2:00PM UTC | 3:00PM CET*
*Program is in development and subject to change


The live portion of this conference has concluded and all presentations are now available for purchase on demand. Registrants to the live event may access this content anytime for up to 9 months following the event.

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Keystone Symposia welcomes the global scientific community and aims to connect researchers within and across disciplines to accelerate the advancement of biomedical and life sciences. This form may be used for scientists from low- and middle-income countries of all career stages to determine eligibility and request free access to scientific content presented during recent eSymposia events. If eligible, you will be sent an access code for the On Demand content of the eSymposia event(s) of interest.

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Lipid metabolism provides the building blocks for cell growth and replication, signaling molecules that initiate and propagate signals inside and outside of cells, and fuel for cell function and division. The role of these molecular species in human disease has become more apparent with advancements in ability to detect and accurately quantify them. This meeting will integrate information generated through lipidomics studies. Specific areas of focus will include using genetic and proteomic data to identify changes in particular molecular species, the importance of changes in lipid metabolism and signaling and the regulatory enzymes for neurodegeneration, metabolic disorders, cancer and inflammation and immune responses. Featured talks will extend beyond methodologies to integrate the current biological and clinical importance of lipids with lipidomics approaches. This will allow us to focus upon the mechanistic importance of lipids in neurodegeneration and other neurological disorders, cancer, inflammation and metabolic disorders. By identifying enzymes that regulate changes in lipidomics, new targets for therapeutics can also be identified. This approach is inspired by PI3kinase, where the basic biochemistry has led to the development of effective inhibitors. We hope to discover other targets for lipid enzyme therapeutics. By moving towards lipid analysis and the biological and medical importance of lipid regulatory pathways, the goal is to use lipidomic profiling to get to better understand and treat different diseases. The majority of lipid related meetings focus on methodologies. We believe that PI3kinase should be reintegrated into meetings about lipid-related disease because it represents successful implementation of this approach. The PI3Kinase specific meeting is no longer attracting sufficient attendees but it remains an important scientific area for discussion. This meeting will also address the importance of particular lipid molecular as opposed to lipid classes. Modern lipidomic methodologies enabled us to identify more than 20,000 potential lipid species in a cell. There are particular species that regulate enzyme activities and membrane properties and thus functions like signaling and cellular migration. This meeting will include a workshop, led by members of LIPID MAPS, on lipidomics methodologies, data handling and storage to further emphasize the biological and medical importance of lipid diversity.

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Regular Registration Rate: $275 USD
Student Registration Rate: $150 USD


Abstract Submission:
‣ For Short Talk Consideration: Passed
‣ For Poster Booth: Passed
ePoster / SciTalk Submission: Passed
Financial Aid Application: Passed

*Abstract submission is required in order to submit an ePoster and/or Scitalk


In Memoriam

In Memoriam

Michael Wakelam, 1955 - 2020

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It is with very heavy hearts that we say good-bye to meeting co-organizer Michael Wakelam, who passed away on March 31, 2020. As an integral member of the Keystone Symposia Scientific Advisory Board, and involved member of our community, he shaped the scientific conversation both within our organization, and the global scientific community at large, with his leadership, vision and personality. We all mourn the loss of this great scientist, and great friend. He will be missed by all of us here at Keystone Symposia, and also many scientists around the world.

Program Details

Keynote Speaker

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Sarah Spiegel
Virginia Commonwealth University

Speaking at this eSymposia

Nihal Altan-Bonnet

NHLBI, National Institutes of Health, USA

Vytas A. Bankaitis

Texas A&M University, USA

Simon T. Barry

AstraZeneca, UK

Steffany A.L. Bennett

University of Ottawa, Canada

John E. Burke

University of Victoria, Canada

Christine Des Rosiers

Montreal Heart Institute (MHI), Canada

Gilbert Di Paolo

Denali Therapeutics Inc., USA

Eamonn James Dickson

University of California, Davis, USA

Gregory D. Fairn

University of Toronto, Canada

Tony Futerman

Weizmann Institute of Science, Israel

Julian L. Griffin

University of Cambridge, UK

Penelope Hallett

Harvard Medical School, USA

Phillip T. Hawkins

Babraham Institute, UK

Bruce D. Levy

Brigham and Women's Hospital, USA

Michelle M. Mielke

Mayo Clinic, USA

Valerie B. O'Donnell

Cardiff University, UK

Julie D. Saba

University of California, San Francisco, USA

Rachel Saunders-Pullman

Mount Sinai, USA

Jean E. Schaffer

Joslin Diabetes Center, Harvard Medical School, USA

Sarah Spiegel

Virginia Commonwealth University, USA

Robert V. Stahelin

Purdue University, USA

Scott A. Summers

University of Utah, USA

Huiyong Yin

Shanghai Institute of Nutrition and Health, China


This new virtual meeting format came out of difficult circumstances, but your commitment to scientific progress is what inspired us to launch Keystone eSymposia. In these virtual meetings, we are capturing the same innovative essence of our in-person meetings that you've all created as a scientific community. Here, Debbie Johnson, our CEO, explains how we're going to do that.

The views expressed in this eSymposia are those of the participants and not necessarily of the participants’ organizations or of Keystone Symposia.

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