Carlo Condello PhD

Dr. Carlo Condello is an Assistant Professor of Neurology and leads a team of scientists at the Institute for Neurodegenerative Diseases (IND) at UCSF. He develops new animal models and optical imaging methods to study protein misfolding diseases, prion biology, and neuroinflammation in vivo. He brings 15 years experience in neurodegenerative disease and glial biology research. Dr. Condello received his PhD in Neuroscience in 2011 from Northwestern University (Chicago, IL). His graduate work with Dr. Jaime Grutzendler focused on understanding the kinetics and toxicity of β-amyloid deposition and the role of microglia in Alzheimer's disease (AD). Following graduation, the lab moved to Yale University, where Dr. Condello completed a project related to his thesis as a postdoctoral fellow. In 2012, Dr. Condello joined the IND first as a postdoctoral fellow with Dr. Stanley Prusiner, then transitioned to a faculty member in 2015. In his tenure at the IND, he has developed a variety of novel optical-imaging tools including noninvasive in vivo imaging methods using bioluminescent or near-infrared fluorescent genetic reporters of astrocytosis to monitor the kinetics of disease progression and therapeutic intervention in rodent models of AD and prion disease.