Mitochondrial dysfunction has emerged as a key factor in a myriad of diseases, including neurodegenerative and metabolic disorders. Likewise, several diseases have been linked to dysfunctional selective autophagy. Protein aggregates and damaged or superfluous organelles such as mitochondria, ER, peroxisomes, endosomes and lysosomes can be degraded by autophagy in a highly selective manner that plays a key role in cellular homeostasis. The aims of the joint Keystone Symposia conferences on "Mitochondrial Biology" and "Selective Autophagy" were to:
Explore the most up-to-date progress regarding the molecular mechanisms underlying selective autophagy and its link with multiple diseases, including presentations on the autophagic machinery that mediates removal of different types of cargo and dysregulated selective autophagy in diseases, including neurodegenerative and immune diseases;
Present and discuss cutting-edge results regarding how mitochondrial form and function are controlled at the cellular and organismal levels and how the many functions of mitochondria impinge on health and disease states, including cancer;
Discuss how new technologies and experimental approaches, such as imaging, will speed progress in the two fields;
Provide a forum for trainees and junior investigators to learn about current progress and future directions of the field, and to establish discussions and networks with other investigators;
Stimulate collaborations among scientists in each field, and across the two fields.
454 Abstracts – 43 speaker and 411 poster abstracts submitted for the conference;
23 ePosters – 15 ePosters from Z1 and 8 ePosters from Z2 in PDF format;
2 SciTalks – Screencast* video recordings of talks by program speakers;
Meeting Book – PDFs of the published meeting book and all the speaker and poster abstracts presented in alphabetical order by presenter last name
The 100 USD access fee covers our administrative costs. Register to purchase the package; once you purchase, you will have unlimited access to log back into the website to view the content. If you have any questions, please contact our Attendee Services Department at firstname.lastname@example.org.
*What Are Screencast Videos?
A screencast is a digital video recording that captures actions taking place on a computer display. The Keystone Symposia presenters recorded their presentations remotely and provided voice-over narration for their presentation materials.
Static and other audio anomalies are present on some videos due to individual environments at the time of the recordings.
Since the talks were given a second time, they may not be identical to those presented in the meeting sessions.
About Virtual Access
Virtual Access is a Keystone Symposia initiative that is designed to provide access to digital content derived from a popular (often oversubscribed) Keystone Symposia conference. It leverages digital media to extend our face-to-face conferences' reach to the broader scientific community. The intent is to disseminate the latest research and fulfill our existing mandate of catalyzing the advancement of biomedical life sciences by convening high-quality scientific conferences.