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Joint meeting with HIV Pathogenesis and Cure

HIV Vaccines

June 1-4, 2021 | 9:00AM EDT | 1:00PM UTC | 3:00PM CEST*
*Program is in development and subject to change



Joint Meetings

Your registration provides you with access to both the “HIV Vaccines” and “HIV Pathogenesis and Cure” eSymposia events. Use the link below to explore the joint meeting features, including live plenary sessions, On Demand talks, posters, forums, job postings, 1:1 Connect appointments and more. This joint meeting access is designed to facilitate cross-disciplinary insights and collaborations to drive both fields in exciting new directions!

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[Joint Session] Welcoming Remarks and Keynote Session
09:00am - 10:10am Eastern - June 1, 2021 | Room: V300 - Chad Littman
Persephone Borrow, PhD, Co-Chair, University of Oxford; Carine M. Van Lint, PhD, Co-Chair, University of Brussels
Track: [Joint Session] Welcoming Remarks and Keynote Session

Tuesday
Accelerating HIV Vaccine Development to Prevent HIV Infection
09:00am - 09:35am Eastern - June 1, 2021 | Room: V300 - Chad Littman
M. Juliana McElrath, MD, PhD, Fred Hutchinson Cancer Research Center
Track: [Joint Session] Welcoming Remarks and Keynote Session

Tuesday
I Am Nothing Without You: The Rationale for T Cell Plus B Cell Vaccines for HIV
09:35am - 10:10am Eastern - June 1, 2021 | Room: V300 - Chad Littman
Bruce D. Walker, MD, Ragon Institute of MGH, MIT and Harvard
Track: [Joint Session] Welcoming Remarks and Keynote Session

[Joint Session] Breakthrough Technologies
10:10am - 11:45am Eastern - June 1, 2021 | Room: V200 - Ian Loudon
Robert F. Siliciano, MD, PhD, Co-Chair, Johns Hopkins University School of Medicine; Michael R. Betts, PhD, Co-Chair, University of Pennsylvania
Track: [Joint Session] Breakthrough Technologies

Tuesday
Tonsil Organoid Culture System
10:10am - 10:35am Eastern - June 1, 2021 | Room: V200 - Ian Loudon
Mark M. Davis, PhD, Stanford University School of Medicine
Track: [Joint Session] Breakthrough Technologies

Tuesday
What Have We Learned from HIV-Barcoding Technologies?
10:35am - 11:00am Eastern - June 1, 2021 | Room: V200 - Ian Loudon
Guillaume J. Filion, PhD, University of Toronto Scarborough
Track: [Joint Session] Breakthrough Technologies

Tuesday
Short Talk: Spatial Profiling of HIV-1 Transmission in Lymphoid Tissues from Humanized Mice and Human Patients with Single-Cell to Single-Virus Resolution
11:00am - 11:15am Eastern - June 1, 2021 | Room: V200 - Ian Loudon
Collin Kieffer, PhD, University of Illinois at Urbana-Champaign
Track: [Joint Session] Breakthrough Technologies

Tuesday
Short Talk: Visualization of HIV Integration and Latency by CasFISH: In situ Imaging System for Localization of the Provirus and its Transcriptional Regulators in Infected Cells
11:15am - 11:30am Eastern - June 1, 2021 | Room: V200 - Ian Loudon
Fredrick Kizito, PhD, Case Western Reserve University
Track: [Joint Session] Breakthrough Technologies

Tuesday
Short Talk: Evolutionary Dynamics of HIV-1 Reservoir Cells Revealed by a Novel Multi-Dimensional Single-Cell Assay
11:30am - 11:45am Eastern - June 1, 2021 | Room: V200 - Ian Loudon
Matthew Osborn, MS, Ragon Institute of MGH, MIT and Harvard
Track: [Joint Session] Breakthrough Technologies

Insights from Preclinical and Clinical Trials
12:05pm - 02:00pm Eastern - June 1, 2021 | Room: V300 - Chad Littman
M. Juliana McElrath, MD, PhD, Co-Chair, Fred Hutchinson Cancer Research Center; Barton F. Haynes, MD, Co-Chair, Duke Human Vaccine Institute
Track: Insights from Preclinical and Clinical Trials

Tuesday
AMP Trial Results
12:05pm - 12:30pm Eastern - June 1, 2021 | Room: V300 - Chad Littman
Lawrence Corey, MD, Fred Hutchinson Cancer Research Center
Track: Insights from Preclinical and Clinical Trials

Tuesday
Optimizing Adjuvants for Clinical Vaccine Development
12:30pm - 12:55pm Eastern - June 1, 2021 | Room: V300 - Chad Littman
Sandhya Vasan, MD, US Military HIV Research Program
Track: Insights from Preclinical and Clinical Trials

Tuesday
Human Clinical Test of Germline Targeting: Preliminary Report on B-Cell Responses in the IAVI G001 Trial of eOD-GT8 60mer
12:55pm - 01:20pm Eastern - June 1, 2021 | Room: V300 - Chad Littman
William Schief, PhD, International AIDS Vaccine Initiative and The Scripps Research Institute
Track: Insights from Preclinical and Clinical Trials

Tuesday
Accelerated Experimental Medicine Trials for Iterative Vaccine Design
01:20pm - 01:45pm Eastern - June 1, 2021 | Room: V300 - Chad Littman
Robin Shattock, PhD, Imperial College London
Track: Insights from Preclinical and Clinical Trials

Tuesday
Short Talk: Efficacy of a Novel Epithelial Stem Cell-based AIDS Vaccine to Induce Mucosal Immune Responses and Control SIV Transmission in Macaques
01:45pm - 02:00pm Eastern - June 1, 2021 | Room: V300 - Chad Littman
Marie-Claire E. Gauduin, PhD, Texas Biomedical Research Institute
Track: Insights from Preclinical and Clinical Trials

Tuesday
[Joint Session] Career Roundtable
03:00pm - 04:00pm Eastern - June 1, 2021
Devi SenGupta, MD, Panelist, Gilead Sciences, Inc.; Kevin O. Saunders, PhD, Panelist, Duke University; Bruce D. Walker, MD, Panelist, Ragon Institute of MGH, MIT and Harvard
Track: Keystone Symposia Roundtables

Immunogen Design for Broadly Neutralizing Antibody Induction
09:00am - 11:25am Eastern - June 2, 2021 | Room: V300 - Chad Littman
Wilton B. Williams, PhD, Co-Chair, Duke University; Christine N. Daniels, PhD, Co-Chair, Duke University
Track: Immunogen Design for Broadly Neutralizing Antibody Induction

Wednesday
Induction of Neutralizing HIV Antibodies by Native-Like SOSIP Trimers
09:00am - 09:25am Eastern - June 2, 2021 | Room: V300 - Chad Littman
Rogier W. Sanders, PhD, University of Amsterdam and Weill Cornell Medical College
Track: Immunogen Design for Broadly Neutralizing Antibody Induction

Wednesday
Cryo-EM Polyclonal Epitope Mapping as a Tool to Accelerate Immunogen Design
09:25am - 09:50am Eastern - June 2, 2021 | Room: V300 - Chad Littman
Gabriel Ozorowski, PhD, The Scripps Research Institute
Track: Immunogen Design for Broadly Neutralizing Antibody Induction

Wednesday
Structural Details of Antibody Interactions with the HIV-1 Glycan Shield and Implications for Vaccine Design
09:50am - 10:15am Eastern - June 2, 2021 | Room: V300 - Chad Littman
Priyamvada Acharya, PhD, Duke University
Track: Immunogen Design for Broadly Neutralizing Antibody Induction

Wednesday
Vaccine Elicitation of CD4 Binding Site Neutralizing Antibodies in Macaques
10:15am - 10:40am Eastern - June 2, 2021 | Room: V300 - Chad Littman
Kevin O. Saunders, PhD, Duke University
Track: Immunogen Design for Broadly Neutralizing Antibody Induction

Wednesday
Short Talk: Structural Characterization of Affinity Maturation in the HIV-1 Glycan-V3 DH270 Broadly Neutralizing Antibody B Cell Lineage
10:40am - 10:55am Eastern - June 2, 2021 | Room: V300 - Chad Littman
Rory Henderson, PhD, Duke University
Track: Immunogen Design for Broadly Neutralizing Antibody Induction

Wednesday
Short Talk: Exploiting the HIV Glycan Shield Network Topology Towards Immunogen Design
10:55am - 11:10am Eastern - June 2, 2021 | Room: V300 - Chad Littman
Srirupa Chakraborty, PhD, Los Alamos National Laboratory
Track: Immunogen Design for Broadly Neutralizing Antibody Induction

Wednesday
Short Talk: Elicitation of V2 Apex Targeting Neutralizing Antibodies by SIVcpz Envs
11:10am - 11:25am Eastern - June 2, 2021 | Room: V300 - Chad Littman
Ronnie M. Russell, BS, University of Pennsylvania
Track: Immunogen Design for Broadly Neutralizing Antibody Induction

Inducing/Modulating Antibody Effector Functions
11:45am - 02:00pm Eastern - June 2, 2021 | Room: V200 - Ian Loudon
Georgia Tomaras, PhD, Co-Chair, Duke Human Vaccine Institute, ; Jay A. Berzofsky, MD, PhD, Co-Chair, NCI, National Institutes of Health
Track: Inducing/Modulating Antibody Effector Functions

Wednesday
Broadly HIV-1 Neutralizing IgA Antibodies
11:45am - 12:10pm Eastern - June 2, 2021 | Room: V200 - Ian Loudon
Hugo Mouquet, PhD, Institut Pasteur
Track: Inducing/Modulating Antibody Effector Functions

Wednesday
Optimizing Antibodies for Antiviral Activity in vivo
12:10pm - 12:35pm Eastern - June 2, 2021 | Room: V200 - Ian Loudon
Margaret E. Ackerman, PhD, Dartmouth College
Track: Inducing/Modulating Antibody Effector Functions

Wednesday
Single Cell Technologies Indicate Monocyte Expression Profiles Influence HIV Reservoir Size and Vaccine Efficacy
12:35pm - 01:00pm Eastern - June 2, 2021 | Room: V200 - Ian Loudon
Rasmi Thomas, PhD, U.S. Military HIV Research Program
Track: Inducing/Modulating Antibody Effector Functions

Wednesday
Short Talk: Broadly Neutralizing Antibody Recognition of HIV Envelope Epitopes Modulates Effector Function
01:00pm - 01:15pm Eastern - June 2, 2021 | Room: V200 - Ian Loudon
Meredith Phelps, BS, Harvard University
Track: Inducing/Modulating Antibody Effector Functions

Wednesday

Wednesday
Short Talk: IgG Fc Sialylation is Regulated during the Germinal Center Reaction Following Immunization with Different Adjuvants
01:30pm - 01:45pm Eastern - June 2, 2021 | Room: V200 - Ian Loudon
Marc Ehlers, PhD, University of Luebeck
Track: Inducing/Modulating Antibody Effector Functions

Wednesday
Short Talk: Incorporating the Cluster A and V1V2 Targets into a Minimal Structural Unit of HIV-1 Envelope to Elicit Cross-Clade Response with Potent Fc-effector Functions
01:45pm - 02:00pm Eastern - June 2, 2021 | Room: V200 - Ian Loudon
Rebekah T. Sherburn, PhD, Uniformed Services University of the Health Sciences
Track: Inducing/Modulating Antibody Effector Functions

Wednesday
[Joint Session] Meet the Editors Roundtable
04:30pm - 05:30pm Eastern - June 2, 2021
Montserrat Cols-Vidal, PhD, Journal of Experimental Medicine; Zeljko Durdevic, PhD, EMBO Press; Sarah Hamilton, PhD, Cell Reports Medicine; Alison Farrell, PhD, Nature Medicine
Track: Keystone Symposia Roundtables

Optimizing Germinal Center Responses for Broadly Neutralizing Antibody Induction
09:00am - 11:25am Eastern - June 3, 2021 | Room: V300 - Chad Littman
Rogier W. Sanders, PhD, Co-Chair, University of Amsterdam and Weill Cornell Medical College; Kevin O. Saunders, PhD, Co-Chair, Duke University
Track: Optimizing Germinal Center Responses for Broadly Neutralizing Antibody Induction

Thursday
GC Regulation Learning from Mice and Men
09:00am - 09:25am Eastern - June 3, 2021 | Room: V300 - Chad Littman
Michel C. Nussenzweig, MD, PhD, HHMI/Rockefeller University
Track: Optimizing Germinal Center Responses for Broadly Neutralizing Antibody Induction

Thursday
Exploiting the Immunological Environment Supporting HIV-1 BnAb Induction During Infection to Inform Vaccine Design
09:25am - 09:50am Eastern - June 3, 2021 | Room: V300 - Chad Littman
Persephone Borrow, PhD, University of Oxford
Track: Optimizing Germinal Center Responses for Broadly Neutralizing Antibody Induction

Thursday
Designing Immunization Regimens to Promote the Germinal Center Response
09:50am - 10:15am Eastern - June 3, 2021 | Room: V300 - Chad Littman
Darrell J. Irvine, PhD, Massachusetts Institute of Technology
Track: Optimizing Germinal Center Responses for Broadly Neutralizing Antibody Induction

Thursday
Targeting HIV-1 ENV V2-apex bNAb Precursors in Human Ig Knock-in Mouse Models
10:15am - 10:40am Eastern - June 3, 2021 | Room: V300 - Chad Littman
Facundo D. Batista, PhD, Massachusetts Institute of Technology and Harvard University
Track: Optimizing Germinal Center Responses for Broadly Neutralizing Antibody Induction

Thursday
Short Talk: HLA-II Associated Viral Adaptation Impacts the Quantity and Quality of CD4+ T-Cell Responses in HIV-1 Vaccine Recipients
10:40am - 10:55am Eastern - June 3, 2021 | Room: V300 - Chad Littman
Jacob K. Files, BS, University of Alabama Birmingham
Track: Optimizing Germinal Center Responses for Broadly Neutralizing Antibody Induction

Thursday
Short Talk: Sequential Immunization Strategies To Elicit Anti HIV-1 Broadly Neutralizing Antibodies
10:55am - 11:10am Eastern - June 3, 2021 | Room: V300 - Chad Littman
Amelia Escolano, PhD, Rockefeller University
Track: Optimizing Germinal Center Responses for Broadly Neutralizing Antibody Induction

Thursday
Short Talk: Fusion Peptide Priming and Long Trimer Interval Reduces Off-target Antibody Responses Toward the HIV-1 Trimer Base Region
11:10am - 11:25am Eastern - June 3, 2021 | Room: V300 - Chad Littman
Angela Corrigan, BS, NIAID, National Institutes of Health
Track: Optimizing Germinal Center Responses for Broadly Neutralizing Antibody Induction

CD8 T Cell Inducing Vaccines
11:45am - 01:25pm Eastern - June 3, 2021 | Room: V200 - Ian Loudon
Persephone Borrow, PhD, Co-Chair, University of Oxford; Bruce D. Walker, MD, Co-Chair, Ragon Institute of MGH, MIT and Harvard
Track: CD8 T Cell Inducing Vaccines

Thursday
Latest Developments in CMV-Vectored HIV/SIV Vaccines
11:45am - 12:10pm Eastern - June 3, 2021 | Room: V200 - Ian Loudon
Louis J. Picker, MD, Oregon Health & Science University
Track: CD8 T Cell Inducing Vaccines

Thursday
Understanding HLA-E Mediated Antigen Presentation to Inform Vaccine Design
12:10pm - 12:35pm Eastern - June 3, 2021 | Room: V200 - Ian Loudon
Andrew J. McMichael, MD, PhD, Oxford University
Track: CD8 T Cell Inducing Vaccines

Thursday
Design of Vaccines to Elicit Conventional (la)-restricted CD8 T Cell Responses
12:35pm - 01:00pm Eastern - June 3, 2021 | Room: V200 - Ian Loudon
Bette Korber, PhD, Los Alamos National Laboratory
Track: CD8 T Cell Inducing Vaccines

Thursday
CD8+ T Cell Tissue Recirculation and Residency in HIV Infection
01:00pm - 01:25pm Eastern - June 3, 2021 | Room: V200 - Ian Loudon
Michael R. Betts, PhD, University of Pennsylvania
Track: CD8 T Cell Inducing Vaccines

[Joint Session] Therapeutic Vaccines
09:00am - 11:50am Eastern - June 4, 2021 | Room: V100 - Ben Schramm
Bonnie J. Howell, PhD, Co-Chair, Merck & Co., Inc.; Michael R. Betts, PhD, Co-Chair, University of Pennsylvania
Track: [Joint Session] Therapeutic Vaccines

Friday
Therapeutic Vaccines – Preclinical to Clinical Trials
09:00am - 09:25am Eastern - June 4, 2021 | Room: V100 - Ben Schramm
Barbara K. Felber, PhD, NCI, National Institutes of Health
Track: [Joint Session] Therapeutic Vaccines

Friday
Therapeutic Antibody and Vaccine Strategies
09:25am - 09:50am Eastern - June 4, 2021 | Room: V100 - Ben Schramm
Dan H. Barouch, MD, PhD, Beth Israel Deaconess Medical Center
Track: [Joint Session] Therapeutic Vaccines

Friday
HIV Remission in Acutely Treated Populations
09:50am - 10:15am Eastern - June 4, 2021 | Room: V100 - Ben Schramm
Julie Ake, MD, Walter Reed Army Institute of Research
Track: [Joint Session] Therapeutic Vaccines

Friday
Target-Intrinsic CTL Resistance, A Role in Reservoir Persistence?
10:15am - 10:40am Eastern - June 4, 2021 | Room: V100 - Ben Schramm
Brad Jones, PhD, Weill Cornell Medicine
Track: [Joint Session] Therapeutic Vaccines

Friday
AELIX-002: A RCT with HTI Therapeutic Vaccines in Early-Treated HIV
10:40am - 11:05am Eastern - June 4, 2021 | Room: V100 - Ben Schramm
Beatriz Mothe, MD, PhD, IrsiCaixa AIDS Research Institute-HIVACAT
Track: [Joint Session] Therapeutic Vaccines

Friday
Short Talk: Duodenal Tissue-Resident CD8+ T Cells Exhibit Low Cytolytic Molecule Expression and Spatially Localise Away from HIV-Susceptible CD4+ T Cells
11:05am - 11:20am Eastern - June 4, 2021 | Room: V100 - Ben Schramm
Leonard Mvaya, Malawi-Liverpool Wellcome Trust Clinical Research Programme
Track: [Joint Session] Therapeutic Vaccines

Friday
Short Talk: Non-Cytotoxic Signatures Dominate HIV Specific T Cell Responses in Viremic Non-Progression
11:20am - 11:35am Eastern - June 4, 2021 | Room: V100 - Ben Schramm
Amit Kumar Singh, MS, National Institute for Research in Reproductive Health
Track: [Joint Session] Therapeutic Vaccines

Friday
Short Talk: The Contribution of CD8+ T Lymphocytes to HIV/SIV Persistence during ART
11:35am - 11:50am Eastern - June 4, 2021 | Room: V100 - Ben Schramm
Deanna A. Kulpa, PhD, Emory University
Track: [Joint Session] Therapeutic Vaccines