Innate Immunity: Mechanisms and Modulation
April 12-15, 2021 | 8:00AM EDT | 12:00PM UTC | 2:00PM CEST*
*Program is in development and subject to change
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Showing results 1 - 10 of 11
Monday, April 12, 2021
Welcome and Keynote Address
8:00 AM - 8:40 AM EDT
Monday, April 12, 2021Organizer
Kate Fitzgerald, PhD
University of Massachusetts Medical School
Keynote
Hao Wu, PhD
Harvard Medical School, Boston Children's Hospital
Welcome and Keynote Address
Structural Insights into Innate Immune Receptors and Signaling
8:00 AM - 8:40 AM EDT
Monday, April 12, 2021Speaker
Hao Wu, PhD
Harvard Medical School, Boston Children's Hospital
Welcome and Keynote Address
Nucleic Acid Sensing
8:40 AM - 10:25 AM EDT
Monday, April 12, 2021Co-Chairs
Kate Fitzgerald, PhD
University of Massachusetts Medical School
Olivia Majer, PhD
MPI for Infection Biology
Nucleic Acid Sensing
DNA Sensing Pathways
8:40 AM - 9:05 AM EDT
Monday, April 12, 2021Speaker
Andrea Ablasser, MD
Ecole Polytechnique Fédérale de Lausanne, Switzerland
Nucleic Acid Sensing
Therapeutic Modulation of the STING Pathway
9:05 AM - 9:30 AM EDT
Monday, April 12, 2021Speaker
Scott Pesiridis, PhD
GlaxoSmithKline
Nucleic Acid Sensing
Regulation of Inflammation by Nucleic Acid Binding Proteins and Non-Coding RNAs
9:30 AM - 9:55 AM EDT
Monday, April 12, 2021Speaker
Kate Fitzgerald, PhD
University of Massachusetts Medical School
Nucleic Acid Sensing
Short Talk: Cellular Mechanisms of Self Versus Non-Self Discrimination by Nucleic Acid-Sensing Toll-Like Receptors
9:55 AM - 10:10 AM EDT
Monday, April 12, 2021Speaker
Olivia Majer, PhD
MPI for Infection Biology
Nucleic Acid Sensing
Short Talk: How cGAS Is Regulated during Mitosis
10:10 AM - 10:25 AM EDT
Monday, April 12, 2021Speaker
Tuo Li, PhD
UT Southwestern Medical Center
Nucleic Acid Sensing
Innate Immunity Gone Awry
10:45 AM - 12:00 PM EDT
Monday, April 12, 2021Co-Chairs
Kate Fitzgerald, PhD
University of Massachusetts Medical School
Clare Bryant, PhD
University of Cambridge
Innate Immunity Gone Awry
Targeting the PANoptosome for the Treatment of Inflammatory and Infectious Diseases
10:45 AM - 11:10 AM EDT
Monday, April 12, 2021Speaker
Thirumala-Devi Kanneganti, PhD
St. Jude Children's Research Hospital
Innate Immunity Gone Awry
Neutrophil Dysregulation in Systemic Autoimmunity
11:10 AM - 11:35 AM EDT
Monday, April 12, 2021Speaker
Mariana Kaplan, MD
NIAMS, National Institutes of Health
Innate Immunity Gone Awry
Genetic Basis of Autoinflammatory Diseases
11:35 AM - 12:00 PM EDT
Monday, April 12, 2021Speaker
Raphaela Goldbach-Mansky, MD
NIAID, National Institutes of Health
Innate Immunity Gone Awry
Career Roundtable
1:00 PM - 2:00 PM EDT
Monday, April 12, 2021Panelists
Kate Fitzgerald, PhD
University of Massachusetts Medical School
Barbara Rehermann, MD
NIDDK, National Institutes of Health
Scott Pesiridis, PhD
GlaxoSmithKline
Keystone Symposia Roundtables
Tuesday, April 13, 2021
Immunometabolism
8:00 AM - 10:25 AM EDT
Tuesday, April 13, 2021Co-Chairs
Kathryn Moore, PhD
New York University Medical Center
Jennifer Dowling, PhD
Royal College of Surgeons in Ireland
Immunometabolism
Krebs Cycle Repurposed for Cytokines
8:00 AM - 8:25 AM EDT
Tuesday, April 13, 2021Speaker
Luke O'Neill, PhD
Trinity Biomedical Sciences Institute
Immunometabolism
Metabolic Regulation of Macrophage Biology
8:25 AM - 8:50 AM EDT
Tuesday, April 13, 2021Speaker
Tiffany Horng, PhD
ShanghaiTech University
Immunometabolism
Macrophage Function in Metabolic Diseases
8:50 AM - 9:15 AM EDT
Tuesday, April 13, 2021Speaker
Kathryn Moore, PhD
New York University Medical Center
Immunometabolism
Impact of Gut Microbiota on Inflammation and Immunity
9:15 AM - 9:40 AM EDT
Tuesday, April 13, 2021Speaker
Barbara Rehermann, MD
NIDDK, National Institutes of Health
Immunometabolism
Short Talk: Mitochondrial Arginase-2 Is Essential for IL-10 Metabolic Reprogramming of Inflammatory Macrophages
9:40 AM - 9:55 AM EDT
Tuesday, April 13, 2021Speaker
Jennifer Dowling, PhD
Royal College of Surgeons in Ireland
Immunometabolism
Short Talk: Mitochondrial Respiration Contributes to the Interferon Gamma Response in Antigen Presenting Cells
9:55 AM - 10:10 AM EDT
Tuesday, April 13, 2021Speaker
Andrew Olive, PhD
Michigan State University
Immunometabolism
Short Talk: How to Stoke a Fiery Death: Recognition of Gasdermins by Proteases
10:10 AM - 10:25 AM EDT
Tuesday, April 13, 2021Speaker
Tsan Sam Xiao, PhD
Case Western Reserve University
Immunometabolism
Short Talk: Host Succinate Is an Activation Signal for Salmonella Virulence during Intracellular Infection
10:25 AM - 10:40 AM EDT
Tuesday, April 13, 2021Speaker
Gili Rosenberg, MS
Weizmann Institute of Science
Immunometabolism
Inflammatory Cell Death
11:05 AM - 11:55 AM EDT
Tuesday, April 13, 2021Co-Chairs
Lucy Thorne, PhD
University College London
Arturo Zychlinsky, PhD
Max Planck Institute for Infection Biology
Inflammatory Cell Death
NETosis
11:05 AM - 11:30 AM EDT
Tuesday, April 13, 2021Speaker
Arturo Zychlinsky, PhD
Max Planck Institute for Infection Biology
Inflammatory Cell Death
Pores in Membranes
11:30 AM - 11:55 AM EDT
Tuesday, April 13, 2021Speaker
Vishva Dixit, MD
Genentech, Inc.
Inflammatory Cell Death
Meet the Editors Roundtable
1:30 PM - 2:30 PM EDT
Tuesday, April 13, 2021Panelists
Karin Dumstrei
EMBO Press
Kirsty Minton
Nature Publishing
Gaia Trincucci, PhD
Journal of Experimental Medicine
Salvatore Fabbiano, PhD
Cell Press
Marianne Clemence, DPhil
PLOS ONE
Keystone Symposia Roundtables
Wednesday, April 14, 2021
Epigenetics and Gene Regulation
8:00 AM - 10:25 AM EDT
Wednesday, April 14, 2021Co-Chairs
Susan Carpenter, PhD
University of California, Santa Cruz
Kate Jeffrey, PhD
Harvard Medical School
Epigenetics and Gene Regulation
Chromatin modifications as readouts of protein kinase activation and inhibition
8:00 AM - 8:25 AM EDT
Wednesday, April 14, 2021Speaker
Gioacchino Natoli, MD
Humanitas University
Epigenetics and Gene Regulation
Regulation of Inflammation by Long Non-Coding RNAs
8:50 AM - 9:15 AM EDT
Wednesday, April 14, 2021Speaker
Susan Carpenter, PhD
University of California, Santa Cruz
Epigenetics and Gene Regulation
IBD Due to Loss-of-Function Mutations in a Chromatin Reader
9:15 AM - 9:40 AM EDT
Wednesday, April 14, 2021Speaker
Kate Jeffrey, PhD
Harvard Medical School
Epigenetics and Gene Regulation
Short Talk: SCARF1-Induced Efferocytosis Plays an Immunomodulatory Role in Humans
9:40 AM - 9:55 AM EDT
Wednesday, April 14, 2021Speaker
Zaida Ramirez, PhD
University of Massachusetts Medical School
Epigenetics and Gene Regulation
Short Talk: SARS-CoV-2 B.1.1.7 Triggers a Less Potent Innate Immune Response than First Wave Isolates
9:55 AM - 10:10 AM EDT
Wednesday, April 14, 2021Speaker
Lucy Thorne, PhD
University College London
Epigenetics and Gene Regulation
Short Talk: Identifying Mutations and Genes Underlying Severe COVID-19 in Exome Biobanks of Diverse Human Populations
10:10 AM - 10:25 AM EDT
Wednesday, April 14, 2021Speaker
Yuval Itan, PhD
Icahn School of Medicine at Mount Sinai
Epigenetics and Gene Regulation
Innate Immune Defense Against Infection
10:45 AM - 12:00 PM EDT
Wednesday, April 14, 2021Co-Chairs
Megan Orzalli, PhD
University of Massachusetts Medical School
Stacy Horner, PhD
Duke University Medical Center
Innate Immune Defense Against Infection
[NOT AVAILABLE ON DEMAND] Origin of Innate Immune Systems in Bacterial Defense against Phage
10:45 AM - 11:10 AM EDT
Wednesday, April 14, 2021Speaker
Rotem Sorek, PhD
Weizmann Institute of Science
Innate Immune Defense Against Infection
Regulation of Anti-Viral Defense through RNA Methylation
11:10 AM - 11:35 AM EDT
Wednesday, April 14, 2021Speaker
Stacy Horner, PhD
Duke University Medical Center
Innate Immune Defense Against Infection
The Dark Side of Histones
11:35 AM - 12:00 PM EDT
Wednesday, April 14, 2021Speaker
Venizelos Papayannopoulos, PhD
Francis Crick Institute
Innate Immune Defense Against Infection
Thursday, April 15, 2021
Inflammasomes
8:00 AM - 10:45 AM EDT
Thursday, April 15, 2021Co-Chairs
Kate Schroder, PhD
University of Queensland
Ioannis Kienes, MS
University of Hohenheim
Inflammasomes
Innate Immune Responses in Human Myeloid Cells
8:00 AM - 8:25 AM EDT
Thursday, April 15, 2021Speaker
Veit Hornung, MD
Ludwig-Maximilians-University Munich
Inflammasomes
Inflammasomes: From Fundamental Biology to New Therapeutics
8:25 AM - 8:50 AM EDT
Thursday, April 15, 2021Speaker
Kate Schroder, PhD
University of Queensland
Inflammasomes
Inflammasomes and Anti-Bacterial Defense
8:50 AM - 9:15 AM EDT
Thursday, April 15, 2021Speaker
Clare Bryant, PhD
University of Cambridge
Inflammasomes
Short Talk: Mechanism of CARD8 Inflammasome Activation by HIV-1 Protease
9:15 AM - 9:30 AM EDT
Thursday, April 15, 2021Speaker
Liang Shan, PhD
Washington University in St. Louis
Inflammasomes
Short Talk: Inflammasomes within Hyperactive Dendritic Cells Stimulate Durable Anti-Tumor Immunity
9:30 AM - 9:45 AM EDT
Thursday, April 15, 2021Speaker
Dania Zhivaki, PhD
Boston Children's Hospital
Inflammasomes
Short Talk: Evolution-Inspired Redesign of the LPS Receptor Caspase-4 into an Interleukin-1 Converting Enzyme
9:45 AM - 10:00 AM EDT
Thursday, April 15, 2021Speaker
Pascal Devant, MS
Harvard Medical School/Boston Children's Hospital
Inflammasomes
Short Talk: DPP9 Sequesters the NLRP1 C-Terminus to Repress Inflammasome Activation
10:00 AM - 10:15 AM EDT
Thursday, April 15, 2021Speaker
Louis Hollingsworth, BS
Boston Children's/Harvard University
Inflammasomes
Short Talk: DDX3X Links NLRP11 to the Regulation of Type I Interferon Responses and NLRP3 Inflammasome Activation
10:15 AM - 10:30 AM EDT
Thursday, April 15, 2021Speaker
Ioannis Kienes, MS
University of Hohenheim
Inflammasomes
