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Single Cell Biology

March 17-19, 2021 | 10:00AM EDT | 2:00PM UTC | 3:00PM CET*
*Program is in development and subject to change


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Welcome and Keynote Address
10:00am - 10:40am Eastern - March 17, 2021
Shalev Itzkovitz, PhD, Chair, Weizmann Institute of Science; Michael Elowitz, PhD, Keynote, California Institute of Technology
Track: Welcome and Keynote Address

Wednesday
Multicellular Circuit Design: Natural and Synthetic
10:00am - 10:40am Eastern - March 17, 2021
Michael Elowitz, PhD, California Institute of Technology
Track: Welcome and Keynote Address

Single Cell Biology of Mammalian Organs
10:40am - 01:00pm Eastern - March 17, 2021
Arjun Raj, PhD, Co-Chair, University of Pennsylvania; Shalev Itzkovitz, PhD, Co-Chair, Weizmann Institute of Science
Track: Single Cell Biology of Mammalian Organs

Wednesday
Sympathetic Neuroimmune Heterogeneity
10:40am - 11:05am Eastern - March 17, 2021
Ana Domingos, PhD, University of Oxford
Track: Single Cell Biology of Mammalian Organs

Wednesday
Dissecting the Alzheimer's Brain: From Single Cells to Cellular Communities
11:05am - 11:30am Eastern - March 17, 2021
Naomi Habib, PhD, Hebrew University of Jerusalem
Track: Single Cell Biology of Mammalian Organs

Wednesday
Spatial Omics of the Intestinal Epithelium
11:40am - 12:05pm Eastern - March 17, 2021
Shalev Itzkovitz, PhD, Weizmann Institute of Science
Track: Single Cell Biology of Mammalian Organs

Wednesday
[NOT AVAILABLE ON DEMAND] Single Cell Analysis of the Intestine
12:05pm - 12:30pm Eastern - March 17, 2021
Ramnik Xavier, MD, Massachusetts General Hospital
Track: Single Cell Biology of Mammalian Organs

Wednesday
Short Talk: Single Cell Transcriptomics Reveals a Modular Macrophage Structure Conserved Across Organs and Species
12:30pm - 12:45pm Eastern - March 17, 2021
Homaira Hamidzada, BS, University of Toronto, Canada
Track: Single Cell Biology of Mammalian Organs

Wednesday
Short Talk: Single Cell Profiling of Acute Kidney Injury in Mice Highlights Differential Cell Death Programs and Renal Fibrosis Patterns
12:45pm - 01:00pm Eastern - March 17, 2021 | Room: V100 - Ben Schramm
Michael Balzer, MD, University of Pennsylvania
Track: Single Cell Biology of Mammalian Organs

Wednesday
Career Roundtable
02:30pm - 03:30pm Eastern - March 17, 2021
Arjun Raj, PhD, Panelist, University of Pennsylvania; Aaron Streets, PhD, Panelist, University of California, Berkeley; Thale C. Jarvis, PhD, Panelist, Keystone Symposia
Track: Career Roundtable

Novel Technologies in Single Cell Analysis
05:00pm - 08:00pm Eastern - March 17, 2021
Arjun Raj, PhD, Co-Chair, University of Pennsylvania; Aaron Streets, PhD, Co-Chair, University of California, Berkeley
Track: Novel Technologies in Single Cell Analysis

Wednesday
Space Exploration: Elucidating Tissue Biology with Spatial Transcriptomics
05:00pm - 05:25pm Eastern - March 17, 2021
Itai Yanai, PhD, New York University School of Medicine
Track: Novel Technologies in Single Cell Analysis

Wednesday
Single Cell Approaches to Collective Cell Behavior
05:25pm - 05:50pm Eastern - March 17, 2021
Prisca Liberali, PhD, Friedrich Miescher Institute for Biomedical Research
Track: Novel Technologies in Single Cell Analysis

Wednesday
Local and Systemic Cellular Activation in Response to Injury in Axolotl
05:50pm - 06:15pm Eastern - March 17, 2021
Jessica Whited, PhD, Harvard University
Track: Novel Technologies in Single Cell Analysis

Wednesday
Imaging and Sequencing Single Cells
06:40pm - 07:05pm Eastern - March 17, 2021 | Room: V300 - Chad Littman
Aaron Streets, PhD, University of California, Berkeley
Track: Novel Technologies in Single Cell Analysis

Wednesday
Image-Based Transcriptomics in the Spatial Context
07:05pm - 07:30pm Eastern - March 17, 2021 | Room: V300 - Chad Littman
Long Cai, PhD, California Institute of Technology
Track: Novel Technologies in Single Cell Analysis

Wednesday
Short Talk: Single-Molecule Chromatin Fiber Sequencing Exposes Cell and Haplotype-Specific Chromatin Architectures
07:30pm - 07:45pm Eastern - March 17, 2021 | Room: V300 - Chad Littman
Andrew B. Stergachis, MD, PhD, University of Washington
Track: Novel Technologies in Single Cell Analysis

Wednesday
Short Talk: scTRIP: A Method to Identify Chromatin Features Influencing Gene Expression Noise
07:45pm - 08:00pm Eastern - March 17, 2021 | Room: V300 - Chad Littman
Clarice Hong, PhD, Washington University in St Louis
Track: Novel Technologies in Single Cell Analysis

Single Cell Analysis in Pathology
10:00am - 12:30pm Eastern - March 18, 2021
Shalev Itzkovitz, PhD, Co-Chair, Weizmann Institute of Science; Alex K. Shalek, PhD, Co-Chair, Massachusetts Institute of Technology
Track: Single Cell Analysis in Pathology

Thursday
New Tools for Visualizing Cellular Heterogeneity in Cancer
10:00am - 10:25am Eastern - March 18, 2021 | Room: V100 - Ben Schramm
Leeat Keren, PhD, Weizmann Institute of Science
Track: Single Cell Analysis in Pathology

Thursday
Trying to Follow in the Footsteps of Mercator: Constructing a Proteogenomics Liver Atlas
10:25am - 10:50am Eastern - March 18, 2021 | Room: V100 - Ben Schramm
Martin Guilliams, PhD, Ghent University - VIB
Track: Single Cell Analysis in Pathology

Thursday
Optimal Division of Labour Within a Cell Type
10:50am - 11:15am Eastern - March 18, 2021 | Room: V100 - Ben Schramm
Uri Alon, PhD, Weizmann Institute of Science
Track: Single Cell Analysis in Pathology

Thursday
Leveraging Single-Cell Genomics to Understand COVID-19
11:35am - 12:00pm Eastern - March 18, 2021 | Room: V300 - Chad Littman
Alex K. Shalek, PhD, Massachusetts Institute of Technology
Track: Single Cell Analysis in Pathology

Thursday
Short Talk: Time-Resolved Single-Cell RNAseq Profiling Identifies a Novel Fabp5-Expressing Subpopulation of Inflammatory Myeloid Cells in Chronic Spinal Cord Injury
12:00pm - 12:15pm Eastern - March 18, 2021 | Room: V300 - Chad Littman
Regan Hamel, Mphil, University of Cambridge
Track: Single Cell Analysis in Pathology

Thursday
Short Talk: Vascular and Perivascular Cell Profiling Reveals the Molecular and Cellular Bases of Blood-Brain Barrier Heterogeneity
12:15pm - 12:30pm Eastern - March 18, 2021 | Room: V300 - Chad Littman
Sarah Pfau, PhD, Harvard Medical School
Track: Single Cell Analysis in Pathology

Thursday
Meet the Editors Roundtable
02:30pm - 03:30pm Eastern - March 18, 2021
Lucia Morgado Palacin, Panelist, JCB of Rockefeller Press; Maria Polychronidou, PhD, Panelist, Molecular Systems Biology (EMBO Press); Katherine Brown, PhD, Panelist, The Company of Biologists; Ines Alvarez-Garcia, Panelist, PLOS (Public Library of Science); Sheba Agarwal, Panelist, Cell Press; Allison Doerr, PhD, Panelist, Nature Methods
Track: Meet the Editors Roundtable

Computational Approaches
05:00pm - 08:00pm Eastern - March 18, 2021
Shalev Itzkovitz, PhD, Co-Chair, Weizmann Institute of Science; Nancy R. Zhang, PhD, Co-Chair, University of Pennsylvania
Track: Computational Approaches

Thursday
Single Cell Analysis in Cancer
05:00pm - 05:25pm Eastern - March 18, 2021
Arjun Raj, PhD, University of Pennsylvania
Track: Computational Approaches

Thursday
Technology and Applications in Single Cell Analysis
05:25pm - 05:50pm Eastern - March 18, 2021
Stephen Quake, PhD, Stanford University
Track: Computational Approaches

Thursday
Integrative Analysis of Allele-Specific Copy Number and Chromatin Accessibility in Cancer
05:50pm - 06:15pm Eastern - March 18, 2021
Nancy R. Zhang, PhD, University of Pennsylvania
Track: Computational Approaches

Thursday
Modeling and Visualizing RNA Velocity of Single Cells
06:40pm - 07:05pm Eastern - March 18, 2021 | Room: V300 - Chad Littman
Jean Fan, PhD, Johns Hopkins University
Track: Computational Approaches

Thursday
Studying developmental robustness at whole-embryo scale and single-cell resolution
07:05pm - 07:30pm Eastern - March 18, 2021 | Room: V300 - Chad Littman
Cole Trapnell, PhD, University of Washington
Track: Computational Approaches

Thursday
Short Talk: Mapping Single-Cell Atlases throughout Metazoa Unravels Cell Type Evolution
07:30pm - 07:45pm Eastern - March 18, 2021 | Room: V300 - Chad Littman
Bo Wang, PhD, Stanford University
Track: Computational Approaches

Thursday
Short Talk: Accurate Whole-Cell Segmentation of Multiplexed Imaging Data by Combining Large-Scale Data Annotation and Deep Learning
07:45pm - 08:00pm Eastern - March 18, 2021 | Room: V300 - Chad Littman
Noah F. Greenwald, BS, Stanford University
Track: Computational Approaches

Tracking Dynamics of Single Cells
10:00am - 01:00pm Eastern - March 19, 2021
Shalev Itzkovitz, PhD, Co-Chair, Weizmann Institute of Science; Sabrina L. Spencer, PhD, Co-Chair, University of Colorado-Boulder
Track: Tracking Dynamics of Single Cells

Friday
Mapping the Temporal and Spatial Dynamics of the Human Endometrium in vivo and in vitro
10:00am - 10:25am Eastern - March 19, 2021 | Room: V100 - Ben Schramm
Roser Vento-Tormo, PhD, Sanger Wellcome Trust
Track: Tracking Dynamics of Single Cells

Friday
Signaling Dynamics for Cellular Fate Control
10:25am - 10:50am Eastern - March 19, 2021 | Room: V100 - Ben Schramm
Silvia Santos, PhD, Francis Crick Institute
Track: Tracking Dynamics of Single Cells

Friday
Real-Time Visualization of Rapid Escape from Drug Treatment in Single Melanoma Cells
10:50am - 11:15am Eastern - March 19, 2021 | Room: V100 - Ben Schramm
Sabrina L. Spencer, PhD, University of Colorado-Boulder
Track: Tracking Dynamics of Single Cells

Friday
Dissecting transcriptional dynamics in development one burst at a time
11:35am - 12:00pm Eastern - March 19, 2021 | Room: V300 - Chad Littman
Hernan G. Garcia, PhD, University of California Berkeley
Track: Tracking Dynamics of Single Cells

Friday
Short Talk: Optogenetic Manipulation Reveals ERK and AKT Signaling Dynamics Required for ESC Differentiation
12:00pm - 12:15pm Eastern - March 19, 2021 | Room: V300 - Chad Littman
Geethika Arekatla, MS, ETH Zurich, Switzerland
Track: Tracking Dynamics of Single Cells

Friday
Short Talk: Deciphering the Epigenetic Encoding, Heritability, and Plasticity of Transcriptional Cancer Cell States via Single Cell Multi-Omics
12:15pm - 12:30pm Eastern - March 19, 2021 | Room: V300 - Chad Littman
Federico Gaiti, PhD, Weill Cornell Medicine
Track: Tracking Dynamics of Single Cells

Friday
Short Talk: Robust, Coherent and Synchronized Circadian Clock-Controlled Oscillations along Multicellular Filaments of Anabaena cyanobacteria
12:30pm - 12:45pm Eastern - March 19, 2021 | Room: V300 - Chad Littman
Rinat Arbel Goren, PhD, Weizmann Institute of Science
Track: Tracking Dynamics of Single Cells

Friday
Short Talk: From Sequence to Space and Time: Inferring Emergent Epigenetic Processes from Single-Cell Multi-Omics
12:45pm - 01:00pm Eastern - March 19, 2021 | Room: V300 - Chad Littman
Steffen Rulands, PhD, Max Planck Institute for the Physics of Complex Systems
Track: Tracking Dynamics of Single Cells

Fate Tracing of Single Cells
05:00pm - 08:00pm Eastern - March 19, 2021
Arjun Raj, PhD, Co-Chair, University of Pennsylvania; John Isaac Murray, PhD, Co-Chair, University of Pennsylvania
Track: Fate Tracing of Single Cells

Friday
High-Throughput Lineage Tracing in the Regenerating Zebrafish Heart
05:00pm - 05:25pm Eastern - March 19, 2021 | Room: V100 - Ben Schramm
Philipp Junker, PhD, Max Delbrück Center for Molecular Medicine
Track: Fate Tracing of Single Cells

Friday
Connecting Cellular States to Cellular Fates
05:25pm - 05:50pm Eastern - March 19, 2021 | Room: V100 - Ben Schramm
Allon M. Klein, PhD, Harvard University
Track: Fate Tracing of Single Cells

Friday
New Genomic Technologies to Measure and Manipulate Cell Identity
05:50pm - 06:15pm Eastern - March 19, 2021 | Room: V100 - Ben Schramm
Samantha A. Morris, PhD, Washington University in St Louis
Track: Fate Tracing of Single Cells

Friday
Decoding Animal Development at Single Cell Resolution
06:40pm - 07:05pm Eastern - March 19, 2021
John Isaac Murray, PhD, University of Pennsylvania
Track: Fate Tracing of Single Cells

Friday
Short Talk: Detangling DNA: Single-Cell Approaches to Understanding Plasticity in Cellular Reprogramming
07:05pm - 07:20pm Eastern - March 19, 2021
Katie Galloway, PhD, Massachusetts Institute of Technology
Track: Fate Tracing of Single Cells

Friday
Short Talk: Clonal Tracking and Expression Profiling in the Mouse Brain via Single Cell and Spatial Transcriptomics
07:20pm - 07:35pm Eastern - March 19, 2021
Michael Ratz, PhD, Karolinska Institutet
Track: Fate Tracing of Single Cells

Friday
Short Talk: Impaired Differentiation: Understanding a Single Cell State Transition
07:35pm - 07:50pm Eastern - March 19, 2021
Merrit J. Romeike, MS, Max Perutz Labs Vienna
Track: Fate Tracing of Single Cells

Friday
Closing Remarks
07:50pm - 08:00pm Eastern - March 19, 2021
Arjun Raj, PhD, Organizer, University of Pennsylvania
Track: Fate Tracing of Single Cells