custom image

Proteomics in Cell Biology and Disease

September 21–23, 2020
*Program is subject to change


Reset

Advanced Filters
Introductory Remarks and Keynote Address
10:00am - 10:40am Eastern - September 21, 2020
Jennie R. Lill, PhD, Chair, Genentech, Inc.
Track: Introductory Remarks and Keynote Address

Monday
Organizer Introductory Remarks
10:00am - 10:05am Eastern - September 21, 2020
Jennie R. Lill, PhD, Genentech, Inc.; Kathryn S. Lilley, PhD, University of Cambridge; Forest M. White, PhD, Massachusetts Institute of Technology
Track: Opening Remarks and Keynote Address

Monday
Proximity Labeling for Mapping Spatial Proteomes and Transcriptomes in Living Cells
10:10am - 10:40am Eastern - September 21, 2020
Alice Y. Ting, PhD, Stanford University
Track: Keynote Address

Studying the Cell Surfaceome
10:40am - 12:35pm Eastern - September 21, 2020
Nadia Martinez-Martin, PhD, Co-Chair, Genentech, Inc.; Gavin J. Wright, PhD, Co-Chair, Wellcome Trust Sanger Institute
Track: Studying the Cell Surfaceome

Monday
Mapping the Human Immunoglobulin Superfamily Receptome to Identify Novel Cancer-Relevant Pathways
10:40am - 11:05am Eastern - September 21, 2020
Nadia Martinez-Martin, PhD, Genentech, Inc.
Track: Studying the Cell Surfaceome

Monday
Light-Mediated Discovery of Surfaceome Nanoscale Organization and Inter-Cellular Receptor Interaction Networks
11:05am - 11:30am Eastern - September 21, 2020
Track: Studying the Cell Surfaceome

Monday
Large-Scale Systematic Approaches to Identify Novel Receptor-Ligand Pairs that Initiate Intercellular Signaling
11:40am - 12:05pm Eastern - September 21, 2020
Gavin J. Wright, PhD, Wellcome Trust Sanger Institute
Track: Studying the Cell Surfaceome

Monday
Short Talk: Identification of Palmitoyl Protein Thioesterase Substrates Defines Roles for Synaptic Depalmitoylation
12:05pm - 12:20pm Eastern - September 21, 2020
Sofia Massaro Tieze, Yale University
Track: Studying the Cell Surfaceome

Monday
Short Talk: Matrisome Signatures in GBM Heterogeneity
12:20pm - 12:35pm Eastern - September 21, 2020
Monika Vishnoi, PhD, Houston Methodist Research Institute
Track: Studying the Cell Surfaceome

Lightning Talks
12:35pm - 01:00pm Eastern - September 21, 2020
Kathryn S. Lilley, PhD, Chair, University of Cambridge
Track: Lightning Talks

Monday
Advanced Multiplex Protein Analysis of Obesity-Related Cardiometabolic Biomarkers in Human Plasma and Serum
12:35pm - 12:38pm Eastern - September 21, 2020
Emma Borgeson, PhD, University of Gothenburg
Track: Lightning Talks

Monday
Ultraviolet Photodissociation Mass Spectrometry Enables Precise Mapping of O-GlcNAc Sites in Proteins
12:38pm - 12:41pm Eastern - September 21, 2020
Dustin T. King, PhD, Simon Fraser University
Track: Lightning Talks

Monday
Spatial Dynamics of the DNA Damage Proteome
12:41pm - 12:44pm Eastern - September 21, 2020
Josie Amber Christopher, BS, University of Cambridge
Track: Lightning Talks

Monday
Proteomic Analysis of Cerebrospinal Fluid in Alzheimer’s Disease
12:47pm - 12:50pm Eastern - September 21, 2020
Justin McKetney, BS, University of Wisconsin-Madison
Track: Lightning Talks

Monday
Deep Protein Arginine Methylation Profiling by LC-MS Proteomics
12:50pm - 12:53pm Eastern - September 21, 2020
Track: Lightning Talks

Dissection of Complex Data Sets: Informatic and Statistical Tools of the Trade
04:00pm - 07:00pm Eastern - September 21, 2020
Lennart Martens, PhD, Co-Chair, Ghent University; Olga Vitek, PhD, Co-Chair, Northeastern University
Track: Dissection of Complex Data Sets: Informatic and Statistical Tools of the Trade

Monday
Integrative Proteogenomics Deconvoluting the Landscape of Lung Adenocarcinoma in Never-Smokers
04:00pm - 04:25pm Eastern - September 21, 2020
Jyoti Choudhary, PhD, Institute of Cancer Research
Track: Dissection of Complex Data Sets: Informatic and Statistical Tools of the Trade

Monday
Machine Learning Powered Next-Generation Proteomics
04:25pm - 04:50pm Eastern - September 21, 2020
Lennart Martens, PhD, Ghent University
Track: Dissection of Complex Data Sets: Informatic and Statistical Tools of the Trade

Monday
Challenges in Large-Scale Computational Mass Spectrometry and Multiomics
04:50pm - 05:15pm Eastern - September 21, 2020
Olga Vitek, PhD, Northeastern University
Track: Dissection of Complex Data Sets: Informatic and Statistical Tools of the Trade

Monday
Phenotyping Cellular States with Functional Proteomics
05:35pm - 06:00pm Eastern - September 21, 2020
Mikhail Savitski, PhD, European Molecular Biology Laboratory
Track: Dissection of Complex Data Sets: Informatic and Statistical Tools of the Trade

Monday
Short Talk: Hu.MAP2.0: Integration of over 15,000 Proteomic Experiments Builds a Global Compendium of Human Multiprotein Assemblies
06:00pm - 06:15pm Eastern - September 21, 2020
Kevin Drew, PhD, University of Texas at Austin
Track: Dissection of Complex Data Sets: Informatic and Statistical Tools of the Trade

Monday
Short Talk: Quantitative Phosphoproteomics Uncovers Dysregulated Kinase Networks in Alzheimer’s Disease
06:15pm - 06:30pm Eastern - September 21, 2020
Nader Morshed, BS, Massachusetts Institute of Technology
Track: Dissection of Complex Data Sets: Informatic and Statistical Tools of the Trade

Monday
Short Talk: Millisecond Informatics: Real-Time Analytics for Quantitative Proteomics
06:30pm - 06:45pm Eastern - September 21, 2020
Devin K. Schweppe, PhD, University of Washington
Track: Dissection of Complex Data Sets: Informatic and Statistical Tools of the Trade

Monday
Short Talk: Designing Methods and Software to Suit the needs of O-glycopeptide Characterization
06:45pm - 07:00pm Eastern - September 21, 2020
Nicholas M. Riley, PhD, Stanford University
Track: Dissection of Complex Data Sets: Informatic and Statistical Tools of the Trade

Working Towards Single Cell Proteomics
10:00am - 01:00pm Eastern - September 22, 2020
Jennie R. Lill, PhD, Co-Chair, Genentech, Inc.; Matthew S. Bogyo, PhD, Co-Chair, Stanford University School of Medicine
Track: Working Towards Single Cell Proteomics

Tuesday
Chemical Proteomic Tools for Identification and Imaging of Enzymes Involved in Cancer and Infectious Disease
10:00am - 10:25am Eastern - September 22, 2020
Matthew S. Bogyo, PhD, Stanford University School of Medicine
Track: Working Towards Single Cell Proteomics

Tuesday
Single Molecule Protein Sequencing
10:25am - 10:50am Eastern - September 22, 2020
Edward M. Marcotte, PhD, University of Texas at Austin
Track: Working Towards Single Cell Proteomics

Tuesday
One Cell at a Time: Nanodroplet Sample Preparation Enables In-Depth Single Cell Proteomics
10:50am - 11:15am Eastern - September 22, 2020
Ryan Kelly, PhD, Brigham Young University
Track: Working Towards Single Cell Proteomics

Tuesday
Discovery and Validation of a Blood-Based Protein Signatures for Assessing Human Health
11:40am - 12:05pm Eastern - September 22, 2020
Joseph Gogain, PhD, SomaLogic, Inc
Track: Working Towards Single Cell Proteomics

Tuesday
Short Talk: Global Phosphoproteome Analysis using FAIMS on a Hybrid Orbitrap Mass Spectrometer
12:05pm - 12:20pm Eastern - September 22, 2020
Laura Muehlbauer, University of Wisconsin-Madison
Track: Working Towards Single Cell Proteomics

Tuesday

Integrative Multidimensional Omics
04:00pm - 07:00pm Eastern - September 22, 2020
Nathalie Agar, PhD, Co-Chair, Brigham and Womens Hospital; Christine Vogel, PhD, Co-Chair, New York University
Track: Integrative Multidimensional Omics

Tuesday
Mass Spectrometry Imaging Methodologies, to Study Neuro-Oncology in Brain Cancer
04:00pm - 04:25pm Eastern - September 22, 2020
Nathalie Agar, PhD, Brigham and Womens Hospital
Track: Integrative Multidimensional Omics

Tuesday
Multidimensional Omics - Harnessing Ribosomal Profiling and Proteomics to Investigate Non Canonical Translation Events in Disease
04:25pm - 04:50pm Eastern - September 22, 2020
Jonathan S. Weissman, PhD, Whitehead Institute and MIT
Track: Integrative Multidimensional Omics

Tuesday
Proteomics for Precision Medicine: A High-Throughput Platform for Proteome and Phospho-Proteome
04:50pm - 05:15pm Eastern - September 22, 2020
Track: Integrative Multidimensional Omics

Tuesday
Short Talk: Multiplexed Proteomics in Macrophages Uncovers Novel Roles of Autophagy in Anti-Microbial Immunity
05:40pm - 05:55pm Eastern - September 22, 2020
Aditya Murthy, PhD, Genentech, Inc.
Track: Integrative Multidimensional Omics

Tuesday
Short Talk: Dynamics of FOXL2 Gene Regulation in the Mouse Ovary
05:55pm - 06:10pm Eastern - September 22, 2020
Roberta Migale, PhD, Francis Crick Institute
Track: Integrative Multidimensional Omics

Tuesday
Short Talk: Dissect RNA-Protein Interactome in Living Cells Using CRISPR-Assisted Proximity Labeling
06:10pm - 06:25pm Eastern - September 22, 2020
Liang Zhang, PhD, City University of Hong Kong
Track: Integrative Multidimensional Omics

Tuesday
Short Talk: Genomic and Multi-Tissue Proteomic Integration for Understanding the Biology of Disease and other Complex Traits
06:25pm - 06:40pm Eastern - September 22, 2020
Carlos Cruchaga, PhD, Washington University School of Medicine
Track: Integrative Multidimensional Omics

Tuesday
Short Talk: Integrative Systems Profiling Identifies New Signatures of Neurodegeneration – and Novel Roles of the Core Proteasome
06:40pm - 06:55pm Eastern - September 22, 2020
Christine Vogel, PhD, New York University
Track: Integrative Multidimensional Omics

Spatial Proteomics
10:00am - 01:00pm Eastern - September 23, 2020
Kathryn S. Lilley, PhD, Co-Chair, University of Cambridge; Matthias Trost, PhD, Co-Chair, Newcastle University
Track: Spatial Proteomics

Wednesday
Spatial Organization of the Transcriptome and Proteome
10:00am - 10:25am Eastern - September 23, 2020
Kathryn S. Lilley, PhD, University of Cambridge
Track: Spatial Proteomics

Wednesday
Tracking Spatiotemporal Proteomics in Complex Systems using Proximity Tagging
10:25am - 10:50am Eastern - September 23, 2020
Anne-Claude Gingras, PhD, Lunenfeld-Tanenbaum Research Institute
Track: Spatial Proteomics

Wednesday
Proteome Analysis Identifies Novel Roles for Ubiquitylation in the Innate Immune Response from the Phagosome
10:50am - 11:15am Eastern - September 23, 2020
Matthias Trost, PhD, Newcastle University
Track: Spatial Proteomics

Wednesday
The Human Protein Atlas – Integrated Omics for Single Cell Analysis
11:40am - 12:05pm Eastern - September 23, 2020
Cecilia Lindskog, PhD, Uppsala University
Track: Spatial Proteomics

Wednesday
Short Talk: Dynamic cis-Proteomics Comprehensively Reveals Signal-Dependent Regulators
12:05pm - 12:20pm Eastern - September 23, 2020
Xinying Zong, PhD, St. Jude Children's Research Hospital
Track: Spatial Proteomics

Wednesday

Wednesday
Career Roundtable
02:30pm - 03:30pm Eastern - September 23, 2020
Anne-Claude Gingras, PhD, Lunenfeld-Tanenbaum Research Institute; Marcus Bantscheff, PhD, GlaxoSmithKline; Nathalie Agar, PhD, Brigham and Womens Hospital
Track: Career Roundtable

Speaking at this Roundtable


“Yvonne “Priti “Evan


Anne-Claude Gingras, PhD, Lunenfeld-Tanenbaum Research Institute

Marcus Bantscheff, PhD, GlaxoSmithKline

Nathalie Agar, PhD, Brigham and Womens Hospital



Event Date/Time: Wednesday, September 23, 2:30–3:30PM ET

As part of our commitment to support and train the next generation of scientific leaders from all backgrounds, Keystone Symposia hosts Career Roundtables at selected in-person and virtual conferences. These workshops create a forum for field leaders to provide their unique perspectives on career development, professional pitfalls and the breadth of scientific opportunities available to support trainee scientists. Established researchers are chosen from a broad range of backgrounds (i.e., diverse demographics, career stages and career paths) to reflect a myriad of career paths and experiences. A panel discussion is followed by break out group sessions to enable trainees to interact with each senior scientist in a comfortable small group setting, to address specific questions, allow for mentorship and networking.

For additional career advancement advice, see our Keypoint Blog "Words of Wisdom from Career Roundtables" with tips gleaned from past events on how to launch your career in academia, industry, publishing and beyond. Whether you are a student, post-doc, or early career investigator, check out these pearls of wisdom for all career stages!

https://keypoint.keystonesymposia.org/features/words-of-wisdom-from-career-roundtable-for-students-post-docs/


Elucidation of in vivo Signaling Networks
04:00pm - 07:00pm Eastern - September 23, 2020
Forest M. White, PhD, Co-Chair, Massachusetts Institute of Technology; Marcus Bantscheff, PhD, Co-Chair, GlaxoSmithKline
Track: Elucidation of in vivo Signaling Networks

Wednesday
Phosphoproteomics for Characterization of Therapeutic Resistance Pathways
04:00pm - 04:25pm Eastern - September 23, 2020
Track: Elucidation of in vivo Signaling Networks

Wednesday
Hippo Pathway Deregulation in Cancer
04:25pm - 04:50pm Eastern - September 23, 2020
Jennie R. Lill, PhD, Genentech, Inc.
Track: Elucidation of in vivo Signaling Networks

Wednesday
Personalised Phosphoproteomics – Studying the Exercise Response in Individuals
04:50pm - 05:15pm Eastern - September 23, 2020
David E. James, PhD, University of Sydney
Track: Elucidation of in vivo Signaling Networks

Wednesday
Chemoproteomics for the Elucidation of Signaling Networks
05:35pm - 06:00pm Eastern - September 23, 2020
Marcus Bantscheff, PhD, GlaxoSmithKline
Track: Elucidation of in vivo Signaling Networks

Wednesday
Short Talk: Electrophilic PROTACs that Degrade Nuclear Proteins by Engaging DCAF16
06:00pm - 06:15pm Eastern - September 23, 2020
Xiaoyu Zhang, PhD, The Scripps Research Institute
Track: Elucidation of in vivo Signaling Networks

Wednesday
Short Talk: Distinct Male and Female Phosphoproteomic Signatures Underlie Human Insulin Resistance
06:15pm - 06:30pm Eastern - September 23, 2020
Nida Haider, PhD, Joslin Diabetes Center/ Harvard Medical School
Track: Elucidation of in vivo Signaling Networks

Wednesday
Short Talk: Systematic Identification of Protein Phosphorylation-Mediated Interactions
06:30pm - 06:45pm Eastern - September 23, 2020
Brendan Floyd, University of Texas at Austin
Track: Elucidation of in vivo Signaling Networks

Wednesday
Closing Remarks (Organizers)
06:45pm - 07:00pm Eastern - September 23, 2020