Ubiquitin-proteasome system dysfunction in the liver of severely obese patients with and without type 2 diabetes iconUbiquitin-proteasome system dysfunction in the liver of severely obese patients with and without type 2 diabetes

Ubiquitin-proteasome system dysfunction in the liver of severely obese patients with and without type 2 diabetes

A CRISPR screen identifies a novel regulator of lysosomal enzyme trafficking iconA CRISPR screen identifies a novel regulator of lysosomal enzyme trafficking

A CRISPR screen identifies a novel regulator of lysosomal enzyme trafficking

Platform: Detection of Endogenous Protein Turnover Induced by Targeted Degraders iconPlatform: Detection of Endogenous Protein Turnover Induced by Targeted Degraders

Platform: Detection of Endogenous Protein Turnover Induced by Targeted Degraders

DESIGN OF AT-7519-INSPIRED PROTACS AS THERAPEUTIC AGENTS AGAINST ACUTE MYELOID LEUKEMIA iconDESIGN OF AT-7519-INSPIRED PROTACS AS THERAPEUTIC AGENTS AGAINST ACUTE MYELOID LEUKEMIA

DESIGN OF AT-7519-INSPIRED PROTACS AS THERAPEUTIC AGENTS AGAINST ACUTE MYELOID LEUKEMIA

Mitochondria-Associated Degradation Pathway (MAD) Function beyond the Outer Membrane iconMitochondria-Associated Degradation Pathway (MAD) Function beyond the Outer Membrane

Mitochondria-Associated Degradation Pathway (MAD) Function beyond the Outer Membrane

Hsp90-mediated regulation of DYRK3 couples stress granule disassembly to stress adaptation and cell growth: implications for Amyotrophic Lateral Sclerosis. iconHsp90-mediated regulation of DYRK3 couples stress granule disassembly to stress adaptation and cell growth: implications for Amyotrophic Lateral Sclerosis.

Hsp90-mediated regulation of DYRK3 couples stress granule disassembly to stress adaptation and cell growth: implications for Amyotrophic Lateral Sclerosis.

Serine and threonine phosphorylation marks proteins for degradation by mitochondrial ClpXP iconSerine and threonine phosphorylation marks proteins for degradation by mitochondrial ClpXP

Serine and threonine phosphorylation marks proteins for degradation by mitochondrial ClpXP

Substrate Recruitment to Proteasomal Degradation in Mycobacteria iconSubstrate Recruitment to Proteasomal Degradation in Mycobacteria

Substrate Recruitment to Proteasomal Degradation in Mycobacteria

Protease Machines iconProtease Machines

Protease Machines

Regulation, Substrate Targeting and Reprogramming of the Bacterial ClpC:ClpP Protease iconRegulation, Substrate Targeting and Reprogramming of the Bacterial ClpC:ClpP Protease

Regulation, Substrate Targeting and Reprogramming of the Bacterial ClpC:ClpP Protease