Targeted Protein Degradation: From Small Molecules to Complex Organelles | EK40



Sessions

Ubiquitin-proteasome system dysfunction in the liver of severely obese patients with and without type 2 diabetes

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A CRISPR screen identifies a novel regulator of lysosomal enzyme trafficking

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Platform: Detection of Endogenous Protein Turnover Induced by Targeted Degraders

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DESIGN OF AT-7519-INSPIRED PROTACS AS THERAPEUTIC AGENTS AGAINST ACUTE MYELOID LEUKEMIA

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Mitochondria-Associated Degradation Pathway (MAD) Function beyond the Outer Membrane

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Hsp90-mediated regulation of DYRK3 couples stress granule disassembly to stress adaptation and cell growth: implications for Amyotrophic Lateral Sclerosis.

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Serine and threonine phosphorylation marks proteins for degradation by mitochondrial ClpXP

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Substrate Recruitment to Proteasomal Degradation in Mycobacteria

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Protease Machines iconProtease Machines

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Protease Machines

Co-Chair(s):

Regulation, Substrate Targeting and Reprogramming of the Bacterial ClpC:ClpP Protease

Speaker(s):
  • Tim Clausen, PhD, Research Institute of Molecular Pathology, IMP