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DNA Repair Mechanisms in Cancer

DNA Repair Mechanisms in Cancer
Date
September 22, 2020
Co-Chairs
Ralph Scully, MD, PhD
Beth Israel Deaconess Medical Center
Gaorav Gupta, MD, PhD
University of North Carolina, Chapel Hill
Short Talk: Mechanisms of Mutagenesis Induced by APOBEC3A in Tumors: The Genomic “Twin Paradox”
Date
September 22, 2020
Speaker
Rémi Buisson, PhD
University of California, Irvine
Molecular Interplay between BRCA1-BARD1 Complexes and the 53BP1 Pathway
Date
September 22, 2020
Speaker
J. Ross Chapman, PhD
University of Oxford
Short Talk: Defining the Role of Translesion Synthesis in BRCA1/2-Mutant Cancer Cells
Date
September 22, 2020
Speaker
Alberto Ciccia, PhD
Columbia University
Short Talk: Structure and Function of the WRN Helicase ATPase Domain as a Dependency in MSI-H Cancer Cells
Date
September 22, 2020
Speaker
Madhwesh Coimbatore Ravichandran
Boehringer Ingelheim RCV GmbH & Co KG
Navigating the Genetic Networks Underpinning Genome Integrity
Date
September 22, 2020
Speaker
Daniel Durocher, PhD
Lunenfeld-Tanenbaum Research Institute
Chromatin Accessibility - A New Vulnerability in BRCA Mutant Cancers
Date
September 22, 2020
Speaker
Roger Greenberg, MD, PhD
University of Pennsylvania
Short Talk: The Use of Microhomologies by RAD51 Promotes Genomic Rearrangements between Non Homologous Sequences
Date
September 22, 2020
Speaker
Josée Guirouilh-Barbat, PhD
Institut Cochin
Short Talk: An in vivo Genetic Screen for Tumor Suppressive DNA Damage Responses in Myc-Induced Breast Cancer
Date
September 22, 2020
Speaker
Gaorav Gupta, MD, PhD
University of North Carolina, Chapel Hill
Short Talk: Persistent Broken Chromosome Inheritance Drives Genome Instability
Date
September 22, 2020
Speaker
Timothy C. Humphrey, PhD
University of Oxford
Short Talk: Repression of HR ‘Back-Up’ Pathway Use by BRCA1
Date
September 22, 2020
Speaker
Jo R. Morris, PhD
University of Birmingham
New Players in the Alkylation Damage Response
Date
September 22, 2020
Speaker
Nima Mosammaparast, MD, PhD
Washington University in St. Louis

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