Dr. Rajan Jain is Assistant Professor, Department of Medicine (Cardiology) and Department of Cell & Developmental Biology at Perelman School of Medicine at the University of Pennsylvania. Dr. Jain is a physician-scientist with a research program primarily focused on understanding the mechanisms underlying lineage restriction, with a particular interest on the role of epigenetics and 3D genome organization. A major focus of his laboratory is defining the molecular factors regulating nuclear lamina-chromatin interactions, their impact on development and disease, and the rules governing spatial positioning of the genome. A second focus is on understanding the mechanistic basis of enhancer-promoter interactions and their role in cardiac development and disease, particularly the role of tandem bromodomain proteins and their role in genome organization during cardiac development. He is also a practicing cardiologist attending in the Cardiac Care Unit at the Philadelphia VA Medical Center.