Michael Holmes PhD


Michael Holmes has served as Vice President, Research since July 2015 and currently oversees Sangamo's research activities. He joined Sangamo in May 2001 as a Scientist and became a Team Leader in 2002, focusing on the development of novel cell-based approaches to screen compound libraries. He was promoted to Director, Therapeutic Gene Modification in 2004, and Senior Director in 2009, where he pioneered the use of ZFNs for genome editing in transformed and primary human cells, including hematopoietic stem cells. Dr. Holmes has authored over 55 publications in the field of genome editing and gene regulation, as well as numerous patents. Prior to joining Sangamo, he worked as a post-doctoral fellow in Dr. Gerald Rubin's lab at the University of California, Berkeley. Dr. Holmes received a BS in Molecular Biology from the University of California, San Diego, and his PhD in Molecular and Cell Biology from the University of California, Berkeley.